A novel mouse model of rhabdomyosarcoma underscores the dichotomy of MDM2-ALT1 function in vivo.

Comiskey, D F; Jacob, A G; Sanford, B L; Montes, M; Goodwin, A K; Steiner, H; Matsa, E; Tapia-Santos, A S; Bebee, T W; Grieves, J; La Perle, K; Boyaka, P; Chandler, D S

Comiskey, D F; Jacob, A G; Sanford, B L; Montes, M; Goodwin, A K; Steiner, H; Matsa, E; Tapia-Santos, A S; Bebee, T W; Grieves, J; La Perle, K; Boyaka, P; Chandler, D S.

Afiliação

Comiskey DF; Molecular, Cellular and Developmental Biology Graduate Program and The Center for RNA Biology, The Ohio State University, Columbus, OH, USA.
Jacob AG; Center for Childhood Cancer and Blood Diseases, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Sanford BL; Molecular, Cellular and Developmental Biology Graduate Program and The Center for RNA Biology, The Ohio State University, Columbus, OH, USA.
Montes M; Center for Childhood Cancer and Blood Diseases, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Goodwin AK; Center for Childhood Cancer and Blood Diseases, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Steiner H; Molecular, Cellular and Developmental Biology Graduate Program and The Center for RNA Biology, The Ohio State University, Columbus, OH, USA.
Matsa E; Center for Childhood Cancer and Blood Diseases, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Tapia-Santos AS; Center for Childhood Cancer and Blood Diseases, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Bebee TW; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, USA.
Grieves J; Center for Childhood Cancer and Blood Diseases, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
La Perle K; Molecular, Cellular and Developmental Biology Graduate Program and The Center for RNA Biology, The Ohio State University, Columbus, OH, USA.
Boyaka P; Center for Childhood Cancer and Blood Diseases, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Chandler DS; Molecular, Cellular and Developmental Biology Graduate Program and The Center for RNA Biology, The Ohio State University, Columbus, OH, USA.

Oncogene ; 37(1): 95-106, 2018 01 04.

Article em En | MEDLINE | ID: mdl-28892044

Assuntos

Carcinogênese/genética; Regulação Neoplásica da Expressão Gênica; Camundongos; Proteínas Proto-Oncogênicas c-mdm2/genética; Rabdomiossarcoma/genética; Processamento Alternativo; Animais; Linfócitos B/metabolismo; Proliferação de Células/genética; Feminino; Humanos; Células MCF-7; Masculino; Camundongos Transgênicos; Células NIH 3T3; Neoplasias Experimentais/genética; Neoplasias Experimentais/patologia; Oncogenes; Proteínas Proto-Oncogênicas c-mdm2/metabolismo; Rabdomiossarcoma/patologia; Transdução de Sinais/genética; Baço/citologia; Baço/patologia; Proteína Supressora de Tumor p53/genética; Proteína Supressora de Tumor p53/metabolismo

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Rabdomiossarcoma / Regulação Neoplásica da Expressão Gênica / Proteínas Proto-Oncogênicas c-mdm2 / Carcinogênese / Camundongos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Oncogene Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

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