Diagnosis and management of Zollinger-Ellison syndrome in 2018.
Minerva Endocrinol
; 43(2): 212-220, 2018 Jun.
Article
em En
| MEDLINE
| ID: mdl-28949124
ABSTRACT
Zollinger-Ellison syndrome (ZES) is a clinical syndrome characterized by gastric acid hypersecretion due to the ectopic secretion of gastrin by a gastrinoma, a neuroendocrine tumor (NET) which mostly develops in the duodenum and in the pancreas. This syndrome was first described by Zollinger and Ellison in 1964; if left untreated, ZES can lead to multiple complications mainly due to gastric hypersecretion and some patients can suffer from the complications of an advanced metastatic disease. Although its clinical features are considered typical, the diagnosis of ZES is often challenging for the clinician. A previous review was published in 2005 by our group, but in 12 years many things have changed the diagnostic tools have been improved and many different therapeutical options are now available.
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
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Tipos_de_cancer
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Outros_tipos
Base de dados:
MEDLINE
Assunto principal:
Síndrome de Zollinger-Ellison
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Minerva Endocrinol
Ano de publicação:
2018
Tipo de documento:
Article