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Metformin and insulin impact on clinical outcome in patients with advanced hepatocellular carcinoma receiving sorafenib: Validation study and biological rationale.
Casadei Gardini, Andrea; Faloppi, Luca; De Matteis, Serena; Foschi, Francesco Giuseppe; Silvestris, Nicola; Tovoli, Francesco; Palmieri, Vincenzo; Marisi, Giorgia; Brunetti, Oronzo; Vespasiani-Gentilucci, Umberto; Perrone, Giuseppe; Valgiusti, Martina; Granato, Anna Maria; Ercolani, Giorgio; Negrini, Giulia; Tamburini, Emiliano; Aprile, Giuseppe; Passardi, Alessandro; Santini, Daniele; Cascinu, Stefano; Frassineti, Giovanni Luca; Scartozzi, Mario.
Afiliação
  • Casadei Gardini A; Department of Medical Oncology, Istituto Scientifico Romagnolo per Lo Studio e Cura Dei Tumori (IRST) IRCCS, Meldola, Italy. Electronic address: andrea.casadei@irst.emr.it.
  • Faloppi L; Department of Medical Oncology, University of Cagliari, Italy.
  • De Matteis S; Biosciences Laboratory, Istituto Scientifico Romagnolo per Lo Studio e La Cura Dei Tumori (IRST) IRCCS, Meldola, Italy.
  • Foschi FG; Department of Internal Medicine, Degli Infermi Hospital, Faenza, Italy.
  • Silvestris N; Department of Medical Oncology, National Cancer Institute Giovanni Paolo II, Bari, Italy.
  • Tovoli F; Department of Medical and Surgical Sciences, Sant'Orsola-Malpighi Hospital, University of Bologna, Italy.
  • Palmieri V; Department of Biomedical Sciences and Human Oncology, Clinica Medica A. Murri, University of Bari Medical School, Italy.
  • Marisi G; Biosciences Laboratory, Istituto Scientifico Romagnolo per Lo Studio e La Cura Dei Tumori (IRST) IRCCS, Meldola, Italy.
  • Brunetti O; Department of Medical Oncology, National Cancer Institute Giovanni Paolo II, Bari, Italy.
  • Vespasiani-Gentilucci U; Internal Medicine and Hepatology Unit, Università Campus Bio-Medico, Rome, Italy.
  • Perrone G; Department of Pathology, Università Campus Bio-Medico, Rome, Italy.
  • Valgiusti M; Department of Medical Oncology, Istituto Scientifico Romagnolo per Lo Studio e Cura Dei Tumori (IRST) IRCCS, Meldola, Italy.
  • Granato AM; Immunotherapy Unit, Istituto Scientifico Romagnolo per Lo Studio e Cura Dei Tumori (IRST) IRCCS, Meldola, Italy.
  • Ercolani G; Department of Medical and Surgical Sciences, Sant'Orsola-Malpighi Hospital, University of Bologna, Italy; Department of General Surgery, Morgagni-Pierantoni Hospital, Forlì, Italy.
  • Negrini G; Department of Medical and Surgical Sciences, Sant'Orsola-Malpighi Hospital, University of Bologna, Italy.
  • Tamburini E; Department of Medical Oncology, Infermi Hospital, Rimini, Italy.
  • Aprile G; Department of Oncology, University and General Hospital, Udine, Italy.
  • Passardi A; Department of Medical Oncology, Istituto Scientifico Romagnolo per Lo Studio e Cura Dei Tumori (IRST) IRCCS, Meldola, Italy.
  • Santini D; Medical Oncology Unit, Università Campus Bio-Medico, Rome, Italy.
  • Cascinu S; Modena Cancer Center, Policlinico di Modena, Università di Modena e Reggio Emilia, Italy.
  • Frassineti GL; Department of Medical Oncology, Istituto Scientifico Romagnolo per Lo Studio e Cura Dei Tumori (IRST) IRCCS, Meldola, Italy.
  • Scartozzi M; Department of Medical Oncology, University of Cagliari, Italy.
Eur J Cancer ; 86: 106-114, 2017 11.
Article em En | MEDLINE | ID: mdl-28985579
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Niacinamida / Carcinoma Hepatocelular / Inibidores de Proteínas Quinases / Diabetes Mellitus Tipo 2 / Hipoglicemiantes / Insulina / Neoplasias Hepáticas / Metformina / Antineoplásicos Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged80 País/Região como assunto: Europa Idioma: En Revista: Eur J Cancer Ano de publicação: 2017 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Compostos de Fenilureia / Niacinamida / Carcinoma Hepatocelular / Inibidores de Proteínas Quinases / Diabetes Mellitus Tipo 2 / Hipoglicemiantes / Insulina / Neoplasias Hepáticas / Metformina / Antineoplásicos Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged80 País/Região como assunto: Europa Idioma: En Revista: Eur J Cancer Ano de publicação: 2017 Tipo de documento: Article