Effects of a new synthetic zerumbone pendant derivative (ZPD) on apoptosis induction and anti-migratory effects in human cervical cancer cells.

Saranya, J; Dhanya, B P; Greeshma, Gopalan; Radhakrishnan, K V; Priya, S

Saranya, J; Dhanya, B P; Greeshma, Gopalan; Radhakrishnan, K V; Priya, S.

Afiliação

Saranya J; Chemical Sciences and Technology Division, CSIR - National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Trivandrum 695019, Kerala, India.
Dhanya BP; Chemical Sciences and Technology Division, CSIR - National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Trivandrum 695019, Kerala, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 110001, India.
Greeshma G; Chemical Sciences and Technology Division, CSIR - National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Trivandrum 695019, Kerala, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 110001, India.
Radhakrishnan KV; Chemical Sciences and Technology Division, CSIR - National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Trivandrum 695019, Kerala, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 110001, India. Electronic address: radhu@niist.res.in.
Priya S; Agro-Processing and Technology Division, CSIR - National Institute for Interdisciplinary Science and Technology (CSIR-NIIST), Trivandrum 695019, Kerala, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi 110001, India. Electronic address: priyasulu@gmail.com.

Chem Biol Interact ; 278: 32-39, 2017 Dec 25.

Article em En | MEDLINE | ID: mdl-28987329

Assuntos

Antineoplásicos/farmacologia; Apoptose/efeitos dos fármacos; Sesquiterpenos/farmacologia; Antineoplásicos/química; Caspase 3/metabolismo; Movimento Celular/efeitos dos fármacos; Fragmentação do DNA/efeitos dos fármacos; Regulação para Baixo/efeitos dos fármacos; Feminino; Células HeLa; Humanos; Microscopia de Fluorescência; Paclitaxel/toxicidade; Fosfatidilserinas/metabolismo; Poli(ADP-Ribose) Polimerases/metabolismo; Proteínas Proto-Oncogênicas c-bcl-2/metabolismo; Sesquiterpenos/química; Regulação para Cima/efeitos dos fármacos; Neoplasias do Colo do Útero/metabolismo; Neoplasias do Colo do Útero/patologia; Proteína X Associada a bcl-2/metabolismo

Palavras-chave

Apoptosis; Cell migration; HeLa cells; Zerumbone; Zingiber zerumbet

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Saude_da_mulher / Colo_do_utero / Tipos_de_cancer / Colo_do_utero / Outros_tipos Base de dados: MEDLINE Assunto principal: Sesquiterpenos / Apoptose / Antineoplásicos Limite: Female / Humans Idioma: En Revista: Chem Biol Interact Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Índia

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