Immunization against full-length protein and peptides from the Lutzomyia longipalpis sand fly salivary component maxadilan protects against Leishmania major infection in a murine model.

Wheat, William H; Arthun, Erik N; Spencer, John S; Regan, Daniel P; Titus, Richard G; Dow, Steven W

Wheat, William H; Arthun, Erik N; Spencer, John S; Regan, Daniel P; Titus, Richard G; Dow, Steven W.

Afiliação

Wheat WH; Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, United States; Department of Microbiology, Immunology, Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collin
Arthun EN; Department of Biology, College of Natural Sciences, Colorado State University, Fort Collins, CO 80523, United States.
Spencer JS; Department of Microbiology, Immunology, Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, United States.
Regan DP; Department of Microbiology, Immunology, Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, United States.
Titus RG; Department of Microbiology, Immunology, Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, United States.
Dow SW; Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, United States; Department of Microbiology, Immunology, Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collin

Vaccine ; 35(48 Pt B): 6611-6619, 2017 12 04.

Article em En | MEDLINE | ID: mdl-29079105

Assuntos

Proteínas de Insetos/química; Proteínas de Insetos/imunologia; Leishmaniose Cutânea/prevenção & controle; Peptídeos/imunologia; Saliva/química; Adjuvantes Imunológicos/administração & dosagem; Compostos de Alúmen/administração & dosagem; Animais; Linfócitos T CD4-Positivos/imunologia; Cátions; DNA/química; Modelos Animais de Doenças; Imunização; Proteínas de Insetos/administração & dosagem; Leishmania major/imunologia; Leishmaniose Cutânea/imunologia; Lipossomos/administração & dosagem; Lipossomos/química; Lipossomos/imunologia; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Endogâmicos C3H; Camundongos Endogâmicos C57BL; Peptídeos/administração & dosagem; Psychodidae/química; Psychodidae/imunologia

Palavras-chave

Adjuvants; Cationic Lipid DNA complexes, CLDC; Leishmania; Maxadilan; Saliva; Sand flies; Vaccine

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Peptídeos / Saliva / Leishmaniose Cutânea / Proteínas de Insetos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Vaccine Ano de publicação: 2017 Tipo de documento: Article

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