The 3C protease of enterovirus A71 counteracts the activity of host zinc-finger antiviral protein (ZAP).

Xie, Li; Lu, Baojing; Zheng, Zhenhua; Miao, Yuanjiu; Liu, Yan; Zhang, Yuan; Zheng, Caishang; Ke, Xianliang; Hu, Qinxue; Wang, Hanzhong

Xie, Li; Lu, Baojing; Zheng, Zhenhua; Miao, Yuanjiu; Liu, Yan; Zhang, Yuan; Zheng, Caishang; Ke, Xianliang; Hu, Qinxue; Wang, Hanzhong.

Afiliação

Xie L; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, PR China.
Lu B; University of Chinese Academy of Sciences, Beijing 100049, PR China.
Zheng Z; Department of Microbiology, School of Basic Medical Sciences, Anhui Medical University, Hefei 230032, PR China.
Miao Y; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, PR China.
Liu Y; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, PR China.
Zhang Y; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, PR China.
Zheng C; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, PR China.
Ke X; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, PR China.
Hu Q; CAS Key Laboratory of Special Pathogens and Biosafety, Center for Emerging Infectious Diseases, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, PR China.
Wang H; âState Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, PR China.

J Gen Virol ; 99(1): 73-85, 2018 Jan.

Article em En | MEDLINE | ID: mdl-29182509

Assuntos

Cisteína Endopeptidases/metabolismo; Enterovirus Humano A/enzimologia; Interações Hospedeiro-Patógeno; Proteínas de Ligação a RNA/metabolismo; Proteínas Virais/metabolismo; Replicação Viral; Proteases Virais 3C; Sequência de Aminoácidos; Substituição de Aminoácidos; Animais; Linhagem Celular Tumoral; Cisteína Endopeptidases/genética; Enterovirus Humano A/genética; Regulação da Expressão Gênica; Genes Reporter; Células HEK293; Células HeLa; Humanos; Luciferases/genética; Luciferases/metabolismo; Células Musculares/metabolismo; Células Musculares/virologia; Proteólise; RNA Interferente Pequeno/genética; RNA Interferente Pequeno/metabolismo; Proteínas de Ligação a RNA/antagonistas & inibidores; Proteínas de Ligação a RNA/genética; Células Sf9/imunologia; Células Sf9/virologia; Transdução de Sinais; Spodoptera; Proteínas Virais/genética

Palavras-chave

3C; cleavage; enterovirus A71; zinc finger antiviral protein

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Proteínas Virais / Replicação Viral / Cisteína Endopeptidases / Proteínas de Ligação a RNA / Enterovirus Humano A / Interações Hospedeiro-Patógeno Limite: Animals / Humans Idioma: En Revista: J Gen Virol Ano de publicação: 2018 Tipo de documento: Article

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