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Use of autologous bone marrow cells concentrate enriched with platelet-fibrin on extensor mechanism allograft reconstruction for extensor mechanism failure following total knee arthroplasty.
Giannotti, S; Parchi, P D; Colasanti, G B; Agostini, G; Moreschini, F; Cataldi, C; Ferrata, P; Capanna, R.
Afiliação
  • Giannotti S; U.O.C. Ortopedia e Traumatologia Università degli Studi di Siena
  • Parchi PD; U.O. Ortopedia e Traumatologia Università degli Studi di Pisa
  • Colasanti GB; U.O.C. Ortopedia e Traumatologia Università degli Studi di Siena
  • Agostini G; U.O. Ortopedia e Traumatologia Università degli Studi di Pisa
  • Moreschini F; U.O.C. Ortopedia e Traumatologia Università degli Studi di Siena
  • Cataldi C; U.O.C. Ortopedia e Traumatologia Università degli Studi di Siena
  • Ferrata P; U.O.C. Ortopedia e Traumatologia Università degli Studi di Siena
  • Capanna R; U.O. Ortopedia e Traumatologia Università degli Studi di Pisa
J Biol Regul Homeost Agents ; 31(4 suppl 1): 107-111, 2017.
Article em En | MEDLINE | ID: mdl-29186946
Allografts techniques remain the best reconstructive strategy for chronic extensor mechanism lesions after total knee arthroplasty (3) but outcomes depend strictly on the host tissue-allograft junctions healing. The purpose of this study is to evaluate if modern techniques of adding autologous bone marrow cells concentrate enriched with platelet-rich fibrin, provide better healing of the allograft. We present the case of an 86 years old patient affected by patellar tendon rupture after TKA. A whole extensor mechanism allograft was performed adding a bone marrow cells concentrate enriched with platelet-rich fibrin on the host tissue-allograft junctions. Preoperatively and at each follow-up the value of Knee Society Score and radiographic consolidation signs were recorded. Radiographic controls showed clear signs of consolidation already at 1 months follow-up and a solid fusion at 3 months. This case report describes a valid method to improve healing using a tissue-construct engineered with stem cells and growth factors.
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Coleções: 01-internacional Temas: Transplante_de_medula_ossea Base de dados: MEDLINE Idioma: En Revista: J Biol Regul Homeost Agents Assunto da revista: BIOLOGIA / BIOQUIMICA Ano de publicação: 2017 Tipo de documento: Article
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Coleções: 01-internacional Temas: Transplante_de_medula_ossea Base de dados: MEDLINE Idioma: En Revista: J Biol Regul Homeost Agents Assunto da revista: BIOLOGIA / BIOQUIMICA Ano de publicação: 2017 Tipo de documento: Article