Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.

O'Donnell, Joanne A; Lehman, Jesse; Roderick, Justine E; Martinez-Marin, Dalia; Zelic, Matija; Doran, Ciara; Hermance, Nicole; Lyle, Stephen; Pasparakis, Manolis; Fitzgerald, Katherine A; Marshak-Rothstein, Ann; Kelliher, Michelle A

O'Donnell, Joanne A; Lehman, Jesse; Roderick, Justine E; Martinez-Marin, Dalia; Zelic, Matija; Doran, Ciara; Hermance, Nicole; Lyle, Stephen; Pasparakis, Manolis; Fitzgerald, Katherine A; Marshak-Rothstein, Ann; Kelliher, Michelle A.

Afiliação

O'Donnell JA; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605.
Lehman J; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605.
Roderick JE; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605.
Martinez-Marin D; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605.
Zelic M; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605.
Doran C; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605.
Hermance N; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605.
Lyle S; Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605.
Pasparakis M; Institute for Genetics, Center for Molecular Medicine, University of Cologne, 50931 Cologne, Germany.
Fitzgerald KA; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, 50931 Cologne, Germany; and.
Marshak-Rothstein A; Program in Innate Immunity, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605.
Kelliher MA; Program in Innate Immunity, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605.

J Immunol ; 200(2): 737-748, 2018 01 15.

Article em En | MEDLINE | ID: mdl-29212904

Assuntos

Autoimunidade; Células Dendríticas/imunologia; Células Dendríticas/metabolismo; Imunidade; Inflamação/etiologia; Inflamação/metabolismo; Proteína Serina-Treonina Quinases de Interação com Receptores/genética; Animais; Autoanticorpos/imunologia; Autoimunidade/genética; Linfócitos B/imunologia; Linfócitos B/metabolismo; Citocinas/metabolismo; Modelos Animais de Doenças; Fibrose; Perfilação da Expressão Gênica; Inflamação/patologia; Inflamação/prevenção & controle; Linfadenopatia/genética; Linfadenopatia/imunologia; Linfadenopatia/metabolismo; Linfadenopatia/patologia; Camundongos; Camundongos Knockout; Fator 88 de Diferenciação Mieloide/genética; Fator 88 de Diferenciação Mieloide/metabolismo; Necrose/genética; Necrose/metabolismo; Proteína Serina-Treonina Quinases de Interação com Receptores/deficiência; Proteína Serina-Treonina Quinases de Interação com Receptores/metabolismo; Transdução de Sinais; Receptores Toll-Like/metabolismo

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Células Dendríticas / Autoimunidade / Proteína Serina-Treonina Quinases de Interação com Receptores / Imunidade / Inflamação Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Immunol Ano de publicação: 2018 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google