Your browser doesn't support javascript.
loading
Body Composition in Crohn's Disease and Ulcerative Colitis: Correlation with Disease Severity and Duration.
Yadav, Dawesh P; Kedia, Saurabh; Madhusudhan, Kumble Seetharama; Bopanna, Sawan; Goyal, Sandeep; Jain, Saransh; Vikram, Naval K; Sharma, Raju; Makharia, Govind K; Ahuja, Vineet.
Afiliação
  • Yadav DP; Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi 110029, India.
  • Kedia S; Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi 110029, India.
  • Madhusudhan KS; Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi 110029, India.
  • Bopanna S; Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi 110029, India.
  • Goyal S; Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi 110029, India.
  • Jain S; Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi 110029, India.
  • Vikram NK; Department of Medicine, All India Institute of Medical Sciences, New Delhi 110029, India.
  • Sharma R; Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi 110029, India.
  • Makharia GK; Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi 110029, India.
  • Ahuja V; Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi 110029, India.
Can J Gastroenterol Hepatol ; 2017: 1215035, 2017.
Article em En | MEDLINE | ID: mdl-29226115
BACKGROUND: Results on body composition in Crohn's disease (CD) and ulcerative colitis (UC) have been heterogeneous and are lacking from Asia. Present study assessed body composition in CD/UC and correlated it with disease severity/duration. METHODS: Patients of CD/UC following between Dec 2014 and Dec 2015 who consented for bioimpedance analysis for body fat measurement were included. Lean mass and fat-free mass index (FFMI) were calculated with standard formulae. Visceral fat area (VFA), subcutaneous fat area (SCA), and visceral to subcutaneous fat ratio (VF/SC) were evaluated in CD patients on abdominal CT. RESULTS: Lean mass in CD (n = 44, mean age: 41.2 ± 15.8 years, 73% males) was significantly lower than UC (n = 53, mean age: 33.2 ± 11.2 years, 68% males; 44.2 ± 7.8 versus 48.3 ± 8.4 Kg, p = 0.01). In both UC/CD, disease severity was associated with nonsignificant decline in BMI (UC: 22.1 ± 4.9 versus 20.2 ± 3.2 versus 19.9 ± 3.2 kg/m2, p = 0.23; CD: 22.1 ± 4.2 versus 19.9 ± 2.3 versus 19.7 ± 4.2 kg/m2, p = 0.18) and fat mass (UC: 10.9 ± 8.9 versus 8.1 ± 5.9 versus 5.7 ± 3.6 kg, p = 0.14; CD: 11.2 ± 7 versus 7.9 ± 4.4 versus 7.2 ± 5.9 kg, p = 0.16), and disease duration was associated with significant decline in FFMI (p < 0.05). In CD, disease severity was associated with nonsignificant decline in SCA and increase in VF/SC. CONCLUSIONS: CD patients have lower lean mass than UC. Body fat decreases with increasing disease severity and fat-free mass decreases with increasing disease duration in both UC/CD.
Assuntos

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Composição Corporal / Colite Ulcerativa / Doença de Crohn / Distribuição da Gordura Corporal Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Can J Gastroenterol Hepatol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Índia

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Composição Corporal / Colite Ulcerativa / Doença de Crohn / Distribuição da Gordura Corporal Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Can J Gastroenterol Hepatol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Índia