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Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy.
Marrone, Lara; Poser, Ina; Casci, Ian; Japtok, Julia; Reinhardt, Peter; Janosch, Antje; Andree, Cordula; Lee, Hyun O; Moebius, Claudia; Koerner, Ellen; Reinhardt, Lydia; Cicardi, Maria Elena; Hackmann, Karl; Klink, Barbara; Poletti, Angelo; Alberti, Simon; Bickle, Marc; Hermann, Andreas; Pandey, Udai Bhan; Hyman, Anthony A; Sterneckert, Jared L.
Afiliação
  • Marrone L; DFG-Center for Regenerative Therapies, Technische Universität Dresden, Fetscherstrasse 105, 01307 Dresden, Germany.
  • Poser I; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Casci I; Department of Pediatrics, Division of Child Neurology, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA.
  • Japtok J; Department of Neurology, Technische Universität Dresden, 01307 Dresden, Germany.
  • Reinhardt P; DFG-Center for Regenerative Therapies, Technische Universität Dresden, Fetscherstrasse 105, 01307 Dresden, Germany; Currently at AbbVie Deutschland GmbH & Co KG, Neuroscience Discovery - Biology Department, Knollstrasse, 67061 Ludwigshafen, Germany.
  • Janosch A; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Andree C; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Lee HO; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Moebius C; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Koerner E; DFG-Center for Regenerative Therapies, Technische Universität Dresden, Fetscherstrasse 105, 01307 Dresden, Germany.
  • Reinhardt L; DFG-Center for Regenerative Therapies, Technische Universität Dresden, Fetscherstrasse 105, 01307 Dresden, Germany.
  • Cicardi ME; Department of Pharmacological and Biomolecular Sciences, Centre of Excellence on Neurodegenerative Diseases University of Milan, Milan 20133, Italy.
  • Hackmann K; Currently at AbbVie Deutschland GmbH & Co KG, Neuroscience Discovery - Biology Department, Knollstrasse, 67061 Ludwigshafen, Germany.
  • Klink B; Institut für Klinische Genetik, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
  • Poletti A; Department of Pharmacological and Biomolecular Sciences, Centre of Excellence on Neurodegenerative Diseases University of Milan, Milan 20133, Italy.
  • Alberti S; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Bickle M; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Hermann A; DFG-Center for Regenerative Therapies, Technische Universität Dresden, Fetscherstrasse 105, 01307 Dresden, Germany; Department of Neurology, Technische Universität Dresden, 01307 Dresden, Germany; German Center for Neurodegenerative Diseases (DZNE), 01307 Dresden, Germany.
  • Pandey UB; Department of Pediatrics, Division of Child Neurology, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA; Department of Neurology, Universit
  • Hyman AA; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany.
  • Sterneckert JL; DFG-Center for Regenerative Therapies, Technische Universität Dresden, Fetscherstrasse 105, 01307 Dresden, Germany. Electronic address: jared.sterneckert@tu-dresden.de.
Stem Cell Reports ; 10(2): 375-389, 2018 02 13.
Article em En | MEDLINE | ID: mdl-29358088
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Proteínas de Drosophila / Ribonucleoproteínas Nucleares Heterogêneas Grupo F-H / Proteína FUS de Ligação a RNA / Células-Tronco Pluripotentes Induzidas / Esclerose Lateral Amiotrófica Limite: Animals / Humans Idioma: En Revista: Stem Cell Reports Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Proteínas de Drosophila / Ribonucleoproteínas Nucleares Heterogêneas Grupo F-H / Proteína FUS de Ligação a RNA / Células-Tronco Pluripotentes Induzidas / Esclerose Lateral Amiotrófica Limite: Animals / Humans Idioma: En Revista: Stem Cell Reports Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha