Efficacy of paclitaxel/dexamethasone intra-tumoral delivery in treating orthotopic mouse breast cancer.

Popilski, Hen; Abtew, Esther; Schwendeman, Steven; Domb, Abraham; Stepensky, David

Popilski, Hen; Abtew, Esther; Schwendeman, Steven; Domb, Abraham; Stepensky, David.

Afiliação

Popilski H; Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Abtew E; Institute of Drug Research, School of Pharmacy-Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
Schwendeman S; Department of Pharmaceutical Sciences and Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
Domb A; Institute of Drug Research, School of Pharmacy-Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
Stepensky D; Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel. Electronic address: davidst@exchange.bgu.ac.il.

J Control Release ; 279: 1-7, 2018 06 10.

Article em En | MEDLINE | ID: mdl-29654797

Assuntos

Antineoplásicos Fitogênicos/administração & dosagem; Sistemas de Liberação de Medicamentos; Neoplasias Mamárias Experimentais/tratamento farmacológico; Polímeros/química; Animais; Antineoplásicos Fitogênicos/farmacologia; Dexametasona/administração & dosagem; Relação Dose-Resposta a Droga; Feminino; Injeções; Neoplasias Pulmonares/prevenção & controle; Neoplasias Pulmonares/secundário; Neoplasias Mamárias Experimentais/patologia; Camundongos; Camundongos Endogâmicos BALB C; Paclitaxel/administração & dosagem

Palavras-chave

Dexamethasone; Intra-tumoral implant; Local anti-cancer treatment; Orthotopic model of breast cancer; Paclitaxel; Promoter drugs

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Polímeros / Sistemas de Liberação de Medicamentos / Neoplasias Mamárias Experimentais / Antineoplásicos Fitogênicos Limite: Animals Idioma: En Revista: J Control Release Assunto da revista: FARMACOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Israel

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