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PD-1 blocks lytic granule polarization with concomitant impairment of integrin outside-in signaling in the natural killer cell immunological synapse.
Huang, Yu; Chen, Zhiying; Jang, Joon Hee; Baig, Mirza S; Bertolet, Grant; Schroeder, Casey; Huang, Shengjian; Hu, Qian; Zhao, Yong; Lewis, Dorothy E; Qin, Lidong; Zhu, Michael Xi; Liu, Dongfang.
Afiliação
  • Huang Y; Department of Integrative Biology and Pharmacology, McGovern Medical School, Graduate Program in Cell and Regulatory Biology, the University of Texas Health Science Center at Houston, Houston, Tex; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, Tex.
  • Chen Z; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, Tex; Xiangya Hospital, Xiangya School of Medicine, Central South University, Changsha, China.
  • Jang JH; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, Tex; Department of Nanomedicine, Houston Methodist Research Institute, Houston, Tex.
  • Baig MS; Center for Biosciences and Biomedical Engineering (BSBE), Indian Institute of Technology (IIT), Indore, India.
  • Bertolet G; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, Tex; Department of Pathology and Immunology, Baylor College of Medicine, Houston, Tex.
  • Schroeder C; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, Tex.
  • Huang S; Department of Lymphoma and Myeloma, the University of Texas MD Anderson Cancer Center, Houston, Tex.
  • Hu Q; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, Tex; Key Laboratory of Gene Engineering of the Ministry of Education, Cooperative Innovation Center for High Performance Computing, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
  • Zhao Y; Key Laboratory of Gene Engineering of the Ministry of Education, Cooperative Innovation Center for High Performance Computing, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
  • Lewis DE; Department of Internal Medicine, University of Texas Health Science Center at Houston, Houston, Tex.
  • Qin L; Department of Nanomedicine, Houston Methodist Research Institute, Houston, Tex.
  • Zhu MX; Department of Integrative Biology and Pharmacology, McGovern Medical School, Graduate Program in Cell and Regulatory Biology, the University of Texas Health Science Center at Houston, Houston, Tex. Electronic address: Michael.X.Zhu@uth.tmc.edu.
  • Liu D; Center for Inflammation and Epigenetics, Houston Methodist Research Institute, Houston, Tex; Department of Microbiology and Immunology, Weill Cornell Medical College, Cornell University, New York, NY. Electronic address: dliu2@houstonmethodist.org.
J Allergy Clin Immunol ; 142(4): 1311-1321.e8, 2018 10.
Article em En | MEDLINE | ID: mdl-29679656
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Integrinas / Sinapses Imunológicas / Receptor de Morte Celular Programada 1 Limite: Humans Idioma: En Revista: J Allergy Clin Immunol Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Integrinas / Sinapses Imunológicas / Receptor de Morte Celular Programada 1 Limite: Humans Idioma: En Revista: J Allergy Clin Immunol Ano de publicação: 2018 Tipo de documento: Article