Zipper-like magnetic molecularly imprinted microspheres for on/off-switchable recognition and extraction of 17ß-estradiol from food samples.
Food Chem
; 261: 87-95, 2018 Sep 30.
Article
em En
| MEDLINE
| ID: mdl-29739610
ABSTRACT
Zipper-like on/off-switchable and magnetic molecularly imprinted microspheres (SM-MIMs) were constructed using acrylamide (AAm) and 2-acrylamide-2-methyl propanesulfonic acid (AMPS) as functional monomers for 17ß-estradiol (17ß-E2) recognition and extraction. The imprinted polymer interactions between poly(AAm) (PAAm) and poly(AMPS) (PAMPS) with on/off-switchable property to temperature, exhibited dissociation at relatively higher temperatures (such as 30⯰C) and helped 17ß-E2 enter into imprinted sites, leading to higher binding capability. Conversely, the interpolymer complexes between PAAm and PAMPS formed and blocked 17ß-E2 access to imprinted sites at lower temperature (such as 20⯰C). SM-MIMs were used as dispersive solid phase extraction (SPE) adsorbent with HPLC for 17ß-E2 pretreatment and detection in food samples, and low limit detection (2.52⯵gâ¯L-1) and quantification (10.76⯵gâ¯L-1) with higher recovery were obtained. Therefore, SM-MIMs may be a promising adsorbent for 17ß-E2 pretreatment in food samples owing to its advantages of on/off-switchable recognition, eco-friendly elution, and efficient separation.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Polímeros
/
Estradiol
/
Impressão Molecular
/
Microesferas
Idioma:
En
Revista:
Food Chem
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
China