Glycosyltransferase Gene Expression Identifies a Poor Prognostic Colorectal Cancer Subtype Associated with Mismatch Repair Deficiency and Incomplete Glycan Synthesis.

Noda, Masaru; Okayama, Hirokazu; Tachibana, Kazunoshin; Sakamoto, Wataru; Saito, Katsuharu; Thar Min, Aung Kyi; Ashizawa, Mai; Nakajima, Takahiro; Aoto, Keita; Momma, Tomoyuki; Katakura, Kyoko; Ohki, Shinji; Kono, Koji

Noda, Masaru; Okayama, Hirokazu; Tachibana, Kazunoshin; Sakamoto, Wataru; Saito, Katsuharu; Thar Min, Aung Kyi; Ashizawa, Mai; Nakajima, Takahiro; Aoto, Keita; Momma, Tomoyuki; Katakura, Kyoko; Ohki, Shinji; Kono, Koji.

Afiliação

Noda M; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Fukushima City, Japan.
Okayama H; Department of Breast Surgery, Fukushima Medical University School of Medicine, Fukushima City, Japan.
Tachibana K; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Fukushima City, Japan. okayama@fmu.ac.jp.
Sakamoto W; Department of Breast Surgery, Fukushima Medical University School of Medicine, Fukushima City, Japan.
Saito K; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Fukushima City, Japan.
Thar Min AK; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Fukushima City, Japan.
Ashizawa M; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Fukushima City, Japan.
Nakajima T; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Fukushima City, Japan.
Aoto K; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Fukushima City, Japan.
Momma T; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Fukushima City, Japan.
Katakura K; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Fukushima City, Japan.
Ohki S; Department of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima City, Japan.
Kono K; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Fukushima City, Japan.

Clin Cancer Res ; 24(18): 4468-4481, 2018 09 15.

Article em En | MEDLINE | ID: mdl-29844132

Assuntos

Neoplasias Colorretais/genética; N-Acetilgalactosaminiltransferases/genética; Polissacarídeos/genética; Prognóstico; Neoplasias Encefálicas/genética; Proliferação de Células/efeitos dos fármacos; Neoplasias Colorretais/classificação; Neoplasias Colorretais/tratamento farmacológico; Neoplasias Colorretais/patologia; Intervalo Livre de Doença; Feminino; Fluoruracila/farmacologia; Regulação Neoplásica da Expressão Gênica; Células HCT116; Humanos; Masculino; Análise em Microsséries; Síndromes Neoplásicas Hereditárias/genética; Polissacarídeos/biossíntese; RNA Mensageiro/genética; Transcriptoma/genética; Polipeptídeo N-Acetilgalactosaminiltransferase

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Colon_e_reto Base de dados: MEDLINE Assunto principal: Polissacarídeos / Prognóstico / Neoplasias Colorretais / N-Acetilgalactosaminiltransferases Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão

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