Comparative Effect between Sardine Oil and Fish Oil Rich in Omega-3 Fatty Acids on Hypertension and the Membrane Composition of Adipocytes in SHR Rats.
J Nutr Sci Vitaminol (Tokyo)
; 64(3): 179-184, 2018.
Article
em En
| MEDLINE
| ID: mdl-29962428
ABSTRACT
Omega-3 polyunsaturated fatty acids, have an important role in reducing hypertriglyceridemia, these acids decrease the mortality for Coronary Heart Disease. Very important is the relationship between fatty acid biosynthesis and distribution in organs and tissues involved in insulin resistance and hypertension due to its role in the production of vasoactive eicosanoids and their effects on insulin sensitivity; which is estimated with the HOMA-IR index, which relates the physiological and metabolic behavior of glucose and insulin in the body. The aim of this project was to compare the effect of sardine oil and omega-3 oils rich in polyunsaturated fatty acids EPA (≈30%) and DHA (≈50%) administered for 6 to 8 wk respectively; on the lipid composition of the plasma membrane of epididymal adipocytes in spontaneously hypertensive rats (SHR) and their relation to obesity, insulin resistance and hypertension. The administration of omega-3 enriched oil significantly decreased the HOMA criteria as an insulin resistance indicator compared to the sardine oil.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Temas:
Agentes_cancerigenos
Base de dados:
MEDLINE
Assunto principal:
Óleos de Peixe
/
Ácidos Graxos Ômega-3
/
Hipertensão
Limite:
Animals
Idioma:
En
Revista:
J Nutr Sci Vitaminol (Tokyo)
Ano de publicação:
2018
Tipo de documento:
Article