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CD52 glycan binds the proinflammatory B box of HMGB1 to engage the Siglec-10 receptor and suppress human T cell function.
Bandala-Sanchez, Esther; G Bediaga, Naiara; Goddard-Borger, Ethan D; Ngui, Katrina; Naselli, Gaetano; Stone, Natalie L; Neale, Alana M; Pearce, Lesley A; Wardak, Ahmad; Czabotar, Peter; Haselhorst, Thomas; Maggioni, Andrea; Hartley-Tassell, Lauren A; Adams, Timothy E; Harrison, Leonard C.
Afiliação
  • Bandala-Sanchez E; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia; bandala@wehi.edu.au harrison@wehi.edu.au.
  • G Bediaga N; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia.
  • Goddard-Borger ED; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.
  • Ngui K; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia.
  • Naselli G; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.
  • Stone NL; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia.
  • Neale AM; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.
  • Pearce LA; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia.
  • Wardak A; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.
  • Czabotar P; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia.
  • Haselhorst T; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.
  • Maggioni A; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia.
  • Hartley-Tassell LA; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.
  • Adams TE; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia.
  • Harrison LC; Commonwealth Scientific and Industrial Research Organisation (CSIRO) Manufacturing, Parkville, VIC 3052, Australia.
Proc Natl Acad Sci U S A ; 115(30): 7783-7788, 2018 07 24.
Article em En | MEDLINE | ID: mdl-29997173

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T / Linfócitos T / Proteína HMGB1 / Antígeno CD52 / Lectinas Limite: Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Receptores de Antígenos de Linfócitos T / Linfócitos T / Proteína HMGB1 / Antígeno CD52 / Lectinas Limite: Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article