Structural Determinants of the Dictyostatin Chemotype for Tubulin Binding Affinity and Antitumor Activity Against Taxane- and Epothilone-Resistant Cancer Cells.

Trigili, Chiara; Barasoain, Isabel; Sánchez-Murcia, Pedro A; Bargsten, Katja; Redondo-Horcajo, Mariano; Nogales, Aurora; Gardner, Nicola M; Meyer, Arndt; Naylor, Guy J; Gómez-Rubio, Elena; Gago, Federico; Steinmetz, Michel O; Paterson, Ian; Prota, Andrea E; Díaz, J Fernando

Trigili, Chiara; Barasoain, Isabel; Sánchez-Murcia, Pedro A; Bargsten, Katja; Redondo-Horcajo, Mariano; Nogales, Aurora; Gardner, Nicola M; Meyer, Arndt; Naylor, Guy J; Gómez-Rubio, Elena; Gago, Federico; Steinmetz, Michel O; Paterson, Ian; Prota, Andrea E; Díaz, J Fernando.

Afiliação

Trigili C; Chemical and Physical Biology, Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, E-28040 Madrid, Spain.
Barasoain I; Chemical and Physical Biology, Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, E-28040 Madrid, Spain.
Sánchez-Murcia PA; Área de Farmacología, Departamento de Ciencias Biomédicas, Universidad de Alcalá, Unidad Asociada al IQM (CSIC), Alcalá de Henares, E-28871 Madrid, Spain.
Bargsten K; Department of Biology and Chemistry Laboratory of Biomolecular Research, Paul Scherrer Institut (PSI), 5232 Villigen, Switzerland.
Redondo-Horcajo M; Chemical and Physical Biology, Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, E-28040 Madrid, Spain.
Nogales A; Instituto de Estructura de la Materia, Consejo Superior de Investigaciones Científicas IEM-CSIC, Serrano 121, E-28006 Madrid, Spain.
Gardner NM; University Chemical Laboratory, University of Cambridge, Cambridge CB2 1EW, U.K.
Meyer A; University Chemical Laboratory, University of Cambridge, Cambridge CB2 1EW, U.K.
Naylor GJ; University Chemical Laboratory, University of Cambridge, Cambridge CB2 1EW, U.K.
Gómez-Rubio E; Área de Farmacología, Departamento de Ciencias Biomédicas, Universidad de Alcalá, Unidad Asociada al IQM (CSIC), Alcalá de Henares, E-28871 Madrid, Spain.
Gago F; Área de Farmacología, Departamento de Ciencias Biomédicas, Universidad de Alcalá, Unidad Asociada al IQM (CSIC), Alcalá de Henares, E-28871 Madrid, Spain.
Steinmetz MO; Department of Biology and Chemistry Laboratory of Biomolecular Research, Paul Scherrer Institut (PSI), 5232 Villigen, Switzerland.
Paterson I; University Chemical Laboratory, University of Cambridge, Cambridge CB2 1EW, U.K.
Prota AE; Department of Biology and Chemistry Laboratory of Biomolecular Research, Paul Scherrer Institut (PSI), 5232 Villigen, Switzerland.
Díaz JF; Chemical and Physical Biology, Centro de Investigaciones Biológicas, CSIC, Ramiro de Maeztu 9, E-28040 Madrid, Spain.

ACS Omega ; 1(6): 1192-1204, 2016 Dec 31.

Article em En | MEDLINE | ID: mdl-30023505

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Idioma: En Revista: ACS Omega Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Espanha

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