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Co-inhibition of mTORC1, HDAC and ESR1α retards the growth of triple-negative breast cancer and suppresses cancer stem cells.
Sulaiman, Andrew; McGarry, Sarah; Lam, Ka Mien; El-Sahli, Sara; Chambers, Jason; Kaczmarek, Shelby; Li, Li; Addison, Christina; Dimitroulakos, Jim; Arnaout, Angel; Nessim, Carolyn; Yao, Zemin; Ji, Guang; Song, Haiyan; Liu, Sheng; Xie, Ying; Gadde, Suresh; Li, Xuguang; Wang, Lisheng.
Afiliação
  • Sulaiman A; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • McGarry S; China-Canada Centre of Research for Digestive Diseases, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • Lam KM; Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 725 South Wanping Road, 200032, Shanghai, China.
  • El-Sahli S; Centre for Infection, Immunity and Inflammation, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
  • Chambers J; Ottawa Institute of Systems Biology, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • Kaczmarek S; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • Li L; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • Addison C; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • Dimitroulakos J; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • Arnaout A; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • Nessim C; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • Yao Z; China-Canada Centre of Research for Digestive Diseases, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • Ji G; Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 725 South Wanping Road, 200032, Shanghai, China.
  • Song H; Centre for Infection, Immunity and Inflammation, Faculty of Medicine, University of Ottawa, Ottawa, Canada.
  • Liu S; Ottawa Institute of Systems Biology, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • Xie Y; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • Gadde S; Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, ON, K1H 8L6, Canada.
  • Li X; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, ON, K1H 8M5, Canada.
  • Wang L; Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, ON, K1H 8L6, Canada.
Cell Death Dis ; 9(8): 815, 2018 07 26.
Article em En | MEDLINE | ID: mdl-30050079
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Receptor alfa de Estrogênio / Alvo Mecanístico do Complexo 1 de Rapamicina / Histona Desacetilases Limite: Animals / Female / Humans Idioma: En Revista: Cell Death Dis Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Receptor alfa de Estrogênio / Alvo Mecanístico do Complexo 1 de Rapamicina / Histona Desacetilases Limite: Animals / Female / Humans Idioma: En Revista: Cell Death Dis Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá