Confined Nanopipette Sensing: From Single Molecules, Single Nanoparticles, to Single Cells.
Angew Chem Int Ed Engl
; 58(12): 3706-3714, 2019 03 18.
Article
em En
| MEDLINE
| ID: mdl-30066493
ABSTRACT
Nanopipettes provide a promising confined space that enables advances in electrochemical, optical, and mass spectrometric measurements at the nanoscale. They have been employed to reveal the hidden population properties and dynamics of single molecules and single particles. Moreover, new detection mechanisms based on nanopipettes have led to detailed information on single cells at high spatial and temporal resolution. In this Minireview, we focus on the fabrication and characterization of nanopipettes, summarize their wide applications for the analysis of single entities, and conclude with an outlook for advanced practical sensing.
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1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Nanopartículas
/
Técnicas Eletroquímicas
Idioma:
En
Revista:
Angew Chem Int Ed Engl
Ano de publicação:
2019
Tipo de documento:
Article