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PI3Ka-Akt1-mediated Prdm4 induction in adipose tissue increases energy expenditure, inhibits weight gain, and improves insulin resistance in diet-induced obese mice.
Song, No-Joon; Chang, Seo-Hyuk; Kim, Suji; Panic, Vanja; Jang, Byung-Hyun; Yun, Ui Jeong; Choi, Jin Hee; Li, Zhen; Park, Ki-Moon; Yoon, Jung-Hoon; Kim, Sunghwan; Yoo, Jae Hyuk; Ling, Jing; Thomas, Kirk; Villanueva, Claudio J; Li, Dean Y; Ahn, Jee-Yin; Ku, Jin-Mo; Park, Kye Won.
Afiliação
  • Song NJ; Department of Food Science and Biotechnology, Sungkyunkwan University, Suwon, 16419, Korea.
  • Chang SH; Department of Food Science and Biotechnology, Sungkyunkwan University, Suwon, 16419, Korea.
  • Kim S; Department of Food Science and Biotechnology, Sungkyunkwan University, Suwon, 16419, Korea.
  • Panic V; Department of Biochemistry, University of Utah School of Medicine, 15N Medical Drive East Room 4100, Salt Lake City, UT, 84112, USA.
  • Jang BH; Department of Food Science and Biotechnology, Sungkyunkwan University, Suwon, 16419, Korea.
  • Yun UJ; Department of Food Science and Biotechnology, Sungkyunkwan University, Suwon, 16419, Korea.
  • Choi JH; Department of Food Science and Biotechnology, Sungkyunkwan University, Suwon, 16419, Korea.
  • Li Z; Department of Food Science and Biotechnology, Sungkyunkwan University, Suwon, 16419, Korea.
  • Park KM; Department of Food Science and Biotechnology, Sungkyunkwan University, Suwon, 16419, Korea.
  • Yoon JH; Department of Food Science and Biotechnology, Sungkyunkwan University, Suwon, 16419, Korea.
  • Kim S; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation, Daegu, 41061, Korea.
  • Yoo JH; Department of Medicine, Program in Molecular Medicine, University of Utah, 15 North 2030 East, Salt Lake City, UT, 84112, USA.
  • Ling J; Department of Medicine, Program in Molecular Medicine, University of Utah, 15 North 2030 East, Salt Lake City, UT, 84112, USA.
  • Thomas K; Department of Medicine, Program in Molecular Medicine, University of Utah, 15 North 2030 East, Salt Lake City, UT, 84112, USA.
  • Villanueva CJ; Department of Biochemistry, University of Utah School of Medicine, 15N Medical Drive East Room 4100, Salt Lake City, UT, 84112, USA.
  • Li DY; Department of Medicine, Program in Molecular Medicine, University of Utah, 15 North 2030 East, Salt Lake City, UT, 84112, USA.
  • Ahn JY; Department of Molecular Cell Biology, Samsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon, 16419, Korea.
  • Ku JM; Biomaterials Research and Development Team, Bio-Center, Gyeonggido Business Science Accelerator, Suwon, 16229, Korea. medichem@gbsa.or.kr.
  • Park KW; Department of Food Science and Biotechnology, Sungkyunkwan University, Suwon, 16419, Korea. kwpark@skku.edu.
Cell Death Dis ; 9(9): 876, 2018 08 29.
Article em En | MEDLINE | ID: mdl-30158592
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Resistência à Insulina / Aumento de Peso / Tecido Adiposo / Fosfatidilinositol 3-Quinases / Proteínas de Ligação a DNA / Metabolismo Energético / Proteínas Proto-Oncogênicas c-akt Tipo de estudo: Health_economic_evaluation Limite: Animals Idioma: En Revista: Cell Death Dis Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Resistência à Insulina / Aumento de Peso / Tecido Adiposo / Fosfatidilinositol 3-Quinases / Proteínas de Ligação a DNA / Metabolismo Energético / Proteínas Proto-Oncogênicas c-akt Tipo de estudo: Health_economic_evaluation Limite: Animals Idioma: En Revista: Cell Death Dis Ano de publicação: 2018 Tipo de documento: Article