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Minimal functional driver gene heterogeneity among untreated metastases.
Reiter, Johannes G; Makohon-Moore, Alvin P; Gerold, Jeffrey M; Heyde, Alexander; Attiyeh, Marc A; Kohutek, Zachary A; Tokheim, Collin J; Brown, Alexia; DeBlasio, Rayne M; Niyazov, Juliana; Zucker, Amanda; Karchin, Rachel; Kinzler, Kenneth W; Iacobuzio-Donahue, Christine A; Vogelstein, Bert; Nowak, Martin A.
Afiliação
  • Reiter JG; Canary Center for Cancer Early Detection, Department of Radiology, Stanford University School of Medicine, Palo Alto, CA 94305, USA. johannes.reiter@stanford.edu martin_nowak@harvard.edu.
  • Makohon-Moore AP; Program for Evolutionary Dynamics, Harvard University, Cambridge, MA 02138, USA.
  • Gerold JM; The David M. Rubenstein Center for Pancreatic Cancer Research, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Heyde A; Program for Evolutionary Dynamics, Harvard University, Cambridge, MA 02138, USA.
  • Attiyeh MA; Program for Evolutionary Dynamics, Harvard University, Cambridge, MA 02138, USA.
  • Kohutek ZA; The David M. Rubenstein Center for Pancreatic Cancer Research, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Tokheim CJ; Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Brown A; Department of Biomedical Engineering, Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD 21218, USA.
  • DeBlasio RM; The David M. Rubenstein Center for Pancreatic Cancer Research, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Niyazov J; The David M. Rubenstein Center for Pancreatic Cancer Research, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Zucker A; The David M. Rubenstein Center for Pancreatic Cancer Research, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Karchin R; The David M. Rubenstein Center for Pancreatic Cancer Research, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
  • Kinzler KW; Department of Biomedical Engineering, Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Iacobuzio-Donahue CA; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Vogelstein B; The Ludwig Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Nowak MA; The Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Science ; 361(6406): 1033-1037, 2018 09 07.
Article em En | MEDLINE | ID: mdl-30190408
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Heterogeneidade Genética / Metástase Neoplásica / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Science Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Heterogeneidade Genética / Metástase Neoplásica / Neoplasias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Science Ano de publicação: 2018 Tipo de documento: Article