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Identification of novel benzothiopyranone compounds against Mycobacterium tuberculosis through scaffold morphing from benzothiazinones.
Li, Peng; Wang, Bin; Zhang, Xinwei; Batt, Sarah M; Besra, Gurdyal S; Zhang, Tingting; Ma, Chen; Zhang, Dongfeng; Lin, Ziyun; Li, Gang; Huang, Haihong; Lu, Yu.
Afiliação
  • Li P; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050, PR China; Beijing Key Laboratory of Active Substance Discovery and Druggability Ev
  • Wang B; Beijing Key Laboratory of Drug Resistance Tuberculosis Research, Department of Pharmacology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, 97 Ma Chang Street, Beijing, 101149, PR China.
  • Zhang X; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050, PR China; Beijing Key Laboratory of Active Substance Discovery and Druggability Ev
  • Batt SM; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.
  • Besra GS; School of Biosciences, University of Birmingham, Birmingham B15 2TT, United Kingdom.
  • Zhang T; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050, PR China.
  • Ma C; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050, PR China.
  • Zhang D; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050, PR China; Beijing Key Laboratory of Active Substance Discovery and Druggability Ev
  • Lin Z; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050, PR China; Beijing Key Laboratory of Active Substance Discovery and Druggability Ev
  • Li G; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050, PR China; Beijing Key Laboratory of Active Substance Discovery and Druggability Ev
  • Huang H; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Sciences, 1 Xian Nong Tan Street, Beijing 100050, PR China; Beijing Key Laboratory of Active Substance Discovery and Druggability Ev
  • Lu Y; Beijing Key Laboratory of Drug Resistance Tuberculosis Research, Department of Pharmacology, Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing Chest Hospital, Capital Medical University, 97 Ma Chang Street, Beijing, 101149, PR China. Electronic address: luyu4876@hotmail.com.
Eur J Med Chem ; 160: 157-170, 2018 Dec 05.
Article em En | MEDLINE | ID: mdl-30336450
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Tiazinas / Cumarínicos / Mycobacterium tuberculosis / Antituberculosos Tipo de estudo: Diagnostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Eur J Med Chem Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Tiazinas / Cumarínicos / Mycobacterium tuberculosis / Antituberculosos Tipo de estudo: Diagnostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Eur J Med Chem Ano de publicação: 2018 Tipo de documento: Article