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Trisomy of a Down Syndrome Critical Region Globally Amplifies Transcription via HMGN1 Overexpression.
Mowery, Cody T; Reyes, Jaime M; Cabal-Hierro, Lucia; Higby, Kelly J; Karlin, Kristen L; Wang, Jarey H; Kimmerling, Robert J; Cejas, Paloma; Lim, Klothilda; Li, Hubo; Furusawa, Takashi; Long, Henry W; Pellman, David; Chapuy, Bjoern; Bustin, Michael; Manalis, Scott R; Westbrook, Thomas F; Lin, Charles Y; Lane, Andrew A.
Afiliação
  • Mowery CT; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Reyes JM; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
  • Cabal-Hierro L; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Higby KJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Karlin KL; Verna and Marrs McLean Department of Biochemistry and Molecular Biology and Therapeutic Innovation Center, Baylor College of Medicine, Houston, TX, USA.
  • Wang JH; Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Kimmerling RJ; Koch Institute for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Cejas P; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Lim K; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Li H; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Furusawa T; Laboratory of Metabolism, National Cancer Institute, Bethesda, MD, USA.
  • Long HW; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Pellman D; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA.
  • Chapuy B; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Department of Hematology and Oncology, University Medical Center Göttingen, Göttingen, Germany.
  • Bustin M; Laboratory of Metabolism, National Cancer Institute, Bethesda, MD, USA.
  • Manalis SR; Koch Institute for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Westbrook TF; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA; Verna and Marrs McLean Department of Biochemistry and Molecular Biology and Therapeutic Innovation Center, Baylor College of Medicine, Houston, TX, USA; Department of Molecular and Cellular Biology, Baylor Coll
  • Lin CY; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA; Verna and Marrs McLean Department of Biochemistry and Molecular Biology and Therapeutic Innovation Center, Baylor College of Medicine, Houston, TX, USA.
  • Lane AA; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Broad Institute of Harvard and MIT, Cambridge, MA, USA. Electronic address: andrew_lane@dfci.harvard.edu.
Cell Rep ; 25(7): 1898-1911.e5, 2018 11 13.
Article em En | MEDLINE | ID: mdl-30428356
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Trissomia / Síndrome de Down / Proteína HMGN1 Limite: Animals / Humans Idioma: En Revista: Cell Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Trissomia / Síndrome de Down / Proteína HMGN1 Limite: Animals / Humans Idioma: En Revista: Cell Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos