Cytotoxicity of nimbolide towards multidrug-resistant tumor cells and hypersensitivity via cellular metabolic modulation.

Mahmoud, Nuha; Saeed, Mohamed E M; Sugimoto, Yoshikazu; Klauck, Sabine M; Greten, Henry J; Efferth, Thomas

Mahmoud, Nuha; Saeed, Mohamed E M; Sugimoto, Yoshikazu; Klauck, Sabine M; Greten, Henry J; Efferth, Thomas.

Afiliação

Mahmoud N; Department of Pharmaceutical Biology, Johannes Gutenberg University, Mainz, Germany.
Saeed MEM; Department of Pharmaceutical Biology, Johannes Gutenberg University, Mainz, Germany.
Sugimoto Y; Division of Chemotherapy, Faculty of Pharmacy, Keio University, Tokyo, Japan.
Klauck SM; Division of Cancer Genome Research, German Cancer Research Center, German Cancer Consortium, National Center for Tumor Diseases, Heidelberg, Germany.
Greten HJ; Abel Salazar Institute of Biomedical Sciences, University of Porto, Porto, Portugal.
Efferth T; Heidelberg School of Chinese Medicine, Heidelberg, Germany.

Oncotarget ; 9(87): 35762-35779, 2018 Nov 06.

Article em En | MEDLINE | ID: mdl-30515268

Palavras-chave

HIF1α; MDR; NF-κB; limonoids; reactive oxygen species

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Oncotarget Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google