The islet-expressed Lhx1 transcription factor interacts with Islet-1 and contributes to glucose homeostasis.

Bethea, Maigen; Liu, Yanping; Wade, Alexa K; Mullen, Rachel; Gupta, Rajesh; Gelfanov, Vasily; DiMarchi, Richard; Bhatnagar, Sushant; Behringer, Richard; Habegger, Kirk M; Hunter, Chad S

Bethea, Maigen; Liu, Yanping; Wade, Alexa K; Mullen, Rachel; Gupta, Rajesh; Gelfanov, Vasily; DiMarchi, Richard; Bhatnagar, Sushant; Behringer, Richard; Habegger, Kirk M; Hunter, Chad S.

Afiliação

Bethea M; Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham , Birmingham, Alabama.
Liu Y; Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham , Birmingham, Alabama.
Wade AK; Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham , Birmingham, Alabama.
Mullen R; Department of Genetics, The University of Texas MD Anderson Cancer Center , Houston, Texas.
Gupta R; Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham , Birmingham, Alabama.
Gelfanov V; Department of Chemistry, Indiana University , Bloomington, Indiana.
DiMarchi R; Department of Chemistry, Indiana University , Bloomington, Indiana.
Bhatnagar S; Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham , Birmingham, Alabama.
Behringer R; Department of Genetics, The University of Texas MD Anderson Cancer Center , Houston, Texas.
Habegger KM; Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham , Birmingham, Alabama.
Hunter CS; Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham , Birmingham, Alabama.

Am J Physiol Endocrinol Metab ; 316(3): E397-E409, 2019 03 01.

Article em En | MEDLINE | ID: mdl-30620636

Assuntos

Glicemia/metabolismo; Proteínas com Homeodomínio LIM/metabolismo; Fatores de Transcrição/metabolismo; Animais; Imunoprecipitação da Cromatina; Proteínas de Ligação a DNA/metabolismo; Técnicas de Silenciamento de Genes; Glucagon/genética; Receptor do Peptídeo Semelhante ao Glucagon 1/genética; Proteínas de Homeodomínio/genética; Homeostase; Células Secretoras de Insulina/metabolismo; Proteínas com Domínio LIM/metabolismo; Proteínas com Homeodomínio LIM/genética; Fator de Transcrição MafB/genética; Camundongos; Camundongos Knockout; Polipeptídeo Pancreático/genética; RNA Mensageiro/metabolismo; Somatostatina/genética; Fatores de Transcrição/genética; Regulação para Cima

Palavras-chave

diabetes; glucagon like peptide 1 receptor; islet; transcription factor

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Glicemia / Proteínas com Homeodomínio LIM Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Am J Physiol Endocrinol Metab Assunto da revista: ENDOCRINOLOGIA / FISIOLOGIA / METABOLISMO Ano de publicação: 2019 Tipo de documento: Article

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