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Global Portrait of Protein Targets of Metabolites of the Neurotoxic Compound BIA 10-2474.
Huang, Zhen; Ogasawara, Daisuke; Seneviratne, Uthpala I; Cognetta, Armand B; Am Ende, Christopher W; Nason, Deane M; Lapham, Kimberly; Litchfield, John; Johnson, Douglas S; Cravatt, Benjamin F.
Afiliação
  • Huang Z; Medicine Design, Chemical Biology , Pfizer Worldwide Research and Development , 1 Portland Street , Cambridge , Massachusetts 02139 , United States.
  • Ogasawara D; Department of Chemistry, The Skaggs Institute for Chemical Biology , The Scripps Research Institute , La Jolla , California 92037 , United States.
  • Seneviratne UI; Medicine Design, Chemical Biology , Pfizer Worldwide Research and Development , 1 Portland Street , Cambridge , Massachusetts 02139 , United States.
  • Cognetta AB; Department of Chemistry, The Skaggs Institute for Chemical Biology , The Scripps Research Institute , La Jolla , California 92037 , United States.
  • Am Ende CW; Medicine Design, Medicinal Chemistry , Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
  • Nason DM; Medicine Design, Medicinal Chemistry , Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
  • Lapham K; Medicine Design, Pharmacokinetics, Dynamics and Metabolism , Pfizer Worldwide Research and Development , Eastern Point Road , Groton , Connecticut 06340 , United States.
  • Litchfield J; Medicine Design, Pharmacokinetics, Dynamics and Metabolism , Pfizer Worldwide Research and Development , 1 Portland Street , Cambridge , Massachusetts 02139 , United States.
  • Johnson DS; Medicine Design, Chemical Biology , Pfizer Worldwide Research and Development , 1 Portland Street , Cambridge , Massachusetts 02139 , United States.
  • Cravatt BF; Department of Chemistry, The Skaggs Institute for Chemical Biology , The Scripps Research Institute , La Jolla , California 92037 , United States.
ACS Chem Biol ; 14(2): 192-197, 2019 02 15.
Article em En | MEDLINE | ID: mdl-30702848
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Piridinas / Óxidos N-Cíclicos / Inibidores Enzimáticos / Amidoidrolases Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Piridinas / Óxidos N-Cíclicos / Inibidores Enzimáticos / Amidoidrolases Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: ACS Chem Biol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos