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Modulating native GABAA receptors in medulloblastoma with positive allosteric benzodiazepine-derivatives induces cell death.
Kallay, Laura; Keskin, Havva; Ross, Alexandra; Rupji, Manali; Moody, Olivia A; Wang, Xin; Li, Guanguan; Ahmed, Taukir; Rashid, Farjana; Stephen, Michael Rajesh; Cottrill, Kirsten A; Nuckols, T Austin; Xu, Maxwell; Martinson, Deborah E; Tranghese, Frank; Pei, Yanxin; Cook, James M; Kowalski, Jeanne; Taylor, Michael D; Jenkins, Andrew; Pomeranz Krummel, Daniel A; Sengupta, Soma.
Afiliação
  • Kallay L; Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
  • Keskin H; Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
  • Ross A; Department of Neurology, Emory University School of Medicine, Atlanta, GA, USA.
  • Rupji M; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA.
  • Moody OA; Department of Cell Biology, Emory University School of Medicine, Atlanta, GA, USA.
  • Wang X; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Canada.
  • Li G; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Canada.
  • Ahmed T; Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
  • Rashid F; Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
  • Stephen MR; Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
  • Cottrill KA; Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
  • Nuckols TA; Molecular and Systems Pharmacology Graduate Training Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, USA.
  • Xu M; Molecular and Systems Pharmacology Graduate Training Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, USA.
  • Martinson DE; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.
  • Tranghese F; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA.
  • Pei Y; Electrical and Computer Engineering Department, Boston University, Boston, MA, USA.
  • Cook JM; Center for Cancer and Immunology Research, Brain Tumor Institute, Children's National Medical Center, Washington, DC, USA.
  • Kowalski J; Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, WI, USA.
  • Taylor MD; Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA.
  • Jenkins A; Department of Biostatistics & Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
  • Pomeranz Krummel DA; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Canada.
  • Sengupta S; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Canada.
J Neurooncol ; 142(3): 411-422, 2019 May.
Article em En | MEDLINE | ID: mdl-30725256
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Benzodiazepinas / Neoplasias Cerebelares / Receptores de GABA-A / Meduloblastoma Limite: Humans Idioma: En Revista: J Neurooncol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Benzodiazepinas / Neoplasias Cerebelares / Receptores de GABA-A / Meduloblastoma Limite: Humans Idioma: En Revista: J Neurooncol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos