Endometrial Regeneration in Asherman's Syndrome: Clinical and Translational evidence of Stem Cell Therapies.
Curr Stem Cell Res Ther
; 14(6): 454-459, 2019.
Article
em En
| MEDLINE
| ID: mdl-30760192
ABSTRACT
Asherman's Syndrome or Intrauterine adhesions is an acquired uterine condition where fibrous scarring forms within the uterine cavity, resulting in reduced menstrual flow, pelvic pain and infertility. Until recently, the molecular mechanisms leading to the formation of fibrosis were poorly understood, and the treatment of Asherman's syndrome has largely focused on hysteroscopic resection of adhesions, hormonal therapy, and physical barriers. Numerous studies have begun exploring the molecular mechanisms behind the fibrotic process underlying Asherman's Syndrome as well as the role of stem cells in the regeneration of the endometrium as a treatment modality. The present review offers a summary of available stem cell-based regeneration studies, as well as highlighting current gaps in research.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Temas:
Geral
Base de dados:
MEDLINE
Assunto principal:
Regeneração
/
Endométrio
/
Ginatresia
Limite:
Female
/
Humans
Idioma:
En
Revista:
Curr Stem Cell Res Ther
Assunto da revista:
TERAPEUTICA
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
China