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Hydrogen sulfide inhibits PCSK9 expression through the PI3K/Akt­SREBP­2 signaling pathway to influence lipid metabolism in HepG2 cells.
Xiao, Jun; Bai, Xue-Qin; Liao, Ling; Zhou, Min; Peng, Juan; Xiang, Qiong; Ren, Zhong; Wen, Hong-Yan; Jiang, Zhi-Sheng; Tang, Zhi-Han; Wang, Mei-Mei; Liu, Lu-Shan.
Afiliação
  • Xiao J; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, University of South China, Hengyang, Hunan 421001, P.R. China.
  • Bai XQ; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, University of South China, Hengyang, Hunan 421001, P.R. China.
  • Liao L; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, University of South China, Hengyang, Hunan 421001, P.R. China.
  • Zhou M; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, University of South China, Hengyang, Hunan 421001, P.R. China.
  • Peng J; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, University of South China, Hengyang, Hunan 421001, P.R. China.
  • Xiang Q; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, University of South China, Hengyang, Hunan 421001, P.R. China.
  • Ren Z; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, University of South China, Hengyang, Hunan 421001, P.R. China.
  • Wen HY; Medical College, Hunan University of Chinese Medicine, Changsha, Hunan 410208, P.R. China.
  • Jiang ZS; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, University of South China, Hengyang, Hunan 421001, P.R. China.
  • Tang ZH; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, University of South China, Hengyang, Hunan 421001, P.R. China.
  • Wang MM; Department of Pediatrics, Affiliated Nanhua Hospital, University of South China, Hengyang, Hunan 421001, P.R. China.
  • Liu LS; Institute of Cardiovascular Disease, Key Laboratory for Arteriosclerology of Hunan Province, University of South China, Hengyang, Hunan 421001, P.R. China.
Int J Mol Med ; 43(5): 2055-2063, 2019 May.
Article em En | MEDLINE | ID: mdl-30864739
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Fosfatidilinositol 3-Quinases / Proteínas Proto-Oncogênicas c-akt / Proteína de Ligação a Elemento Regulador de Esterol 2 / Metabolismo dos Lipídeos / Inibidores de PCSK9 / Sulfeto de Hidrogênio Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Int J Mol Med Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Fosfatidilinositol 3-Quinases / Proteínas Proto-Oncogênicas c-akt / Proteína de Ligação a Elemento Regulador de Esterol 2 / Metabolismo dos Lipídeos / Inibidores de PCSK9 / Sulfeto de Hidrogênio Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Int J Mol Med Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2019 Tipo de documento: Article