Prediction and Validation of Immunogenic Domains of Pneumococcal Proteins Recognized by Human CD4<sup>+</sup> T Cells.

van de Garde, Martijn D B; van Westen, Els; Poelen, Martien C M; Rots, Nynke Y; van Els, Cécile A C M

Prediction and Validation of Immunogenic Domains of Pneumococcal Proteins Recognized by Human CD4⁺ T Cells.

van de Garde, Martijn D B; van Westen, Els; Poelen, Martien C M; Rots, Nynke Y; van Els, Cécile A C M.

Afiliação

van de Garde MDB; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.
van Westen E; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.
Poelen MCM; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.
Rots NY; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.
van Els CACM; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands Cecile.van.Els@rivm.nl.

Infect Immun ; 87(6)2019 06.

Article em En | MEDLINE | ID: mdl-30910792

Assuntos

Proteínas de Bactérias/química; Proteínas de Bactérias/imunologia; Linfócitos T CD4-Positivos/imunologia; Infecções Pneumocócicas/microbiologia; Streptococcus pneumoniae/imunologia; Proteínas de Bactérias/genética; Epitopos de Linfócito T/química; Epitopos de Linfócito T/genética; Epitopos de Linfócito T/imunologia; Humanos; Interferon gama/genética; Interferon gama/imunologia; Interleucina-17/genética; Interleucina-17/imunologia; Leucócitos Mononucleares/imunologia; Infecções Pneumocócicas/genética; Infecções Pneumocócicas/imunologia; Domínios Proteicos; Streptococcus pneumoniae/química; Streptococcus pneumoniae/genética

Palavras-chave

CD4+ T cells; HLA-DR restriction; MHC; adaptive immunity; epitope prediction; pneumococcal proteins; pneumococcus, Streptococcus pneumoniae

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Infecções Pneumocócicas / Streptococcus pneumoniae / Proteínas de Bactérias / Linfócitos T CD4-Positivos Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Infect Immun Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Holanda

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