Hsp105&#945; suppresses Adriamycin-induced cell death via nuclear localization signal-dependent nuclear accumulation.

Yamane, Teppei; Saito, Youhei; Teshima, Hiroko; Hagino, Mari; Kakihana, Ayana; Sato, Saki; Shimada, Masashi; Kato, Yoshiho; Kuga, Takahisa; Yamagishi, Nobuyuki; Nakayama, Yuji

Hsp105α suppresses Adriamycin-induced cell death via nuclear localization signal-dependent nuclear accumulation.

Yamane, Teppei; Saito, Youhei; Teshima, Hiroko; Hagino, Mari; Kakihana, Ayana; Sato, Saki; Shimada, Masashi; Kato, Yoshiho; Kuga, Takahisa; Yamagishi, Nobuyuki; Nakayama, Yuji.

Afiliação

Yamane T; Department of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, Kyoto, Japan.
Saito Y; Department of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, Kyoto, Japan.
Teshima H; Department of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, Kyoto, Japan.
Hagino M; Department of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, Kyoto, Japan.
Kakihana A; Department of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, Kyoto, Japan.
Sato S; Department of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, Kyoto, Japan.
Shimada M; Department of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, Kyoto, Japan.
Kato Y; Department of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, Kyoto, Japan.
Kuga T; Department of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, Kyoto, Japan.
Yamagishi N; Department of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, Kyoto, Japan.
Nakayama Y; Department of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, Kyoto, Japan.

J Cell Biochem ; 120(10): 17951-17962, 2019 10.

Article em En | MEDLINE | ID: mdl-31173393

Assuntos

Núcleo Celular/metabolismo; Doxorrubicina/farmacologia; Proteínas de Choque Térmico HSP110/metabolismo; Sinais de Localização Nuclear/metabolismo; Animais; Células COS; Morte Celular/efeitos dos fármacos; Núcleo Celular/efeitos dos fármacos; Proliferação de Células/efeitos dos fármacos; Chlorocebus aethiops; Técnicas de Silenciamento de Genes; Células HEK293; Células HeLa; Humanos; Carioferinas/metabolismo; Transporte Proteico/efeitos dos fármacos; Receptores Citoplasmáticos e Nucleares/metabolismo; Proteína Exportina 1

Palavras-chave

Adriamycin; CRM1; Hsp105; nuclear accumulation; nuclear localization signal

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Doxorrubicina / Núcleo Celular / Sinais de Localização Nuclear / Proteínas de Choque Térmico HSP110 Limite: Animals / Humans Idioma: En Revista: J Cell Biochem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão

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