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Dyads of G-Quadruplex Ligands Triggering DNA Damage Response and Tumour Cell Growth Inhibition at Subnanomolar Concentration.
Doria, Filippo; Salvati, Erica; Pompili, Luca; Pirota, Valentina; D'Angelo, Carmen; Manoli, Francesco; Nadai, Matteo; Richter, Sara N; Biroccio, Annamaria; Manet, Ilse; Freccero, Mauro.
Afiliação
  • Doria F; Department of Chemistry, University of Pavia, V. le Taramelli 10, 27100, Pavia, Italy.
  • Salvati E; Oncogenomic and Epigenetic Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianes 53, 00144, Rome, Italy.
  • Pompili L; Present address: Institute of Molecular Biology and Pathology (IBPM), National Research Council (CNR), Via degli Apuli 4, 00185, Rome, Italy.
  • Pirota V; Oncogenomic and Epigenetic Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianes 53, 00144, Rome, Italy.
  • D'Angelo C; Department of Chemistry, University of Pavia, V. le Taramelli 10, 27100, Pavia, Italy.
  • Manoli F; Oncogenomic and Epigenetic Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianes 53, 00144, Rome, Italy.
  • Nadai M; Institute for Organic Synthesis and Photoreactivity (ISOF), National Research Council (CNR), Via P. Gobetti 101, 40129, Bologna, Italy.
  • Richter SN; Department of Molecular Medicine, University of Padua, Via Gabelli 63, 35121, Padua, Italy.
  • Biroccio A; Department of Molecular Medicine, University of Padua, Via Gabelli 63, 35121, Padua, Italy.
  • Manet I; Oncogenomic and Epigenetic Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianes 53, 00144, Rome, Italy.
  • Freccero M; Institute for Organic Synthesis and Photoreactivity (ISOF), National Research Council (CNR), Via P. Gobetti 101, 40129, Bologna, Italy.
Chemistry ; 25(47): 11085-11097, 2019 Aug 22.
Article em En | MEDLINE | ID: mdl-31219221
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Dano ao DNA / Reparo do DNA / Quadruplex G / Imidas / Naftalenos Limite: Humans Idioma: En Revista: Chemistry Assunto da revista: QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Itália
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Dano ao DNA / Reparo do DNA / Quadruplex G / Imidas / Naftalenos Limite: Humans Idioma: En Revista: Chemistry Assunto da revista: QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Itália