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A structure-based mechanism of cisplatin resistance mediated by glutathione transferase P1-1.
De Luca, Anastasia; Parker, Lorien J; Ang, Wee Han; Rodolfo, Carlo; Gabbarini, Valentina; Hancock, Nancy C; Palone, Francesca; Mazzetti, Anna P; Menin, Laure; Morton, Craig J; Parker, Michael W; Lo Bello, Mario; Dyson, Paul J.
Afiliação
  • De Luca A; Department of Biology, University of Rome Tor Vergata, 00133 Rome, Italy.
  • Parker LJ; Australian Cancer Research Foundation Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia.
  • Ang WH; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC 3010, Australia.
  • Rodolfo C; Department of Chemistry, National University of Singapore, 117506 Singapore.
  • Gabbarini V; Department of Biology, University of Rome Tor Vergata, 00133 Rome, Italy.
  • Hancock NC; Department of Biology, University of Rome Tor Vergata, 00133 Rome, Italy.
  • Palone F; Australian Cancer Research Foundation Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia.
  • Mazzetti AP; Department of Biology, University of Rome Tor Vergata, 00133 Rome, Italy.
  • Menin L; Pediatric Gastroenterology and Liver Unit, Department of Pediatrics, Sapienza University of Rome, 00161 Rome, Italy.
  • Morton CJ; Department of Biology, University of Rome Tor Vergata, 00133 Rome, Italy.
  • Parker MW; Institut des Sciences et Ingénierie Chimiques, École Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
  • Lo Bello M; Australian Cancer Research Foundation Rational Drug Discovery Centre, St. Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia.
  • Dyson PJ; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC 3010, Australia.
Proc Natl Acad Sci U S A ; 116(28): 13943-13951, 2019 07 09.
Article em En | MEDLINE | ID: mdl-31221747

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Cisplatino / Proteínas Quinases JNK Ativadas por Mitógeno / Glutationa S-Transferase pi / Neoplasias Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Cisplatino / Proteínas Quinases JNK Ativadas por Mitógeno / Glutationa S-Transferase pi / Neoplasias Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Itália