Cellular target identification of Withangulatin A using fluorescent analogues and subsequent chemical proteomics.

Zhu, Tianyu; Chen, Chen; Wang, Sisi; Zhang, Yi; Zhu, Dongrong; Li, Lingnan; Luo, Jianguang; Kong, Lingyi

Zhu, Tianyu; Chen, Chen; Wang, Sisi; Zhang, Yi; Zhu, Dongrong; Li, Lingnan; Luo, Jianguang; Kong, Lingyi.

Afiliação

Zhu T; State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. luojg@cpu.edu.cn lykong@cpu.edu.cn.
Chen C; State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. luojg@cpu.edu.cn lykong@cpu.edu.cn.
Wang S; State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. luojg@cpu.edu.cn lykong@cpu.edu.cn.
Zhang Y; State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. luojg@cpu.edu.cn lykong@cpu.edu.cn.
Zhu D; State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. luojg@cpu.edu.cn lykong@cpu.edu.cn.
Li L; State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. luojg@cpu.edu.cn lykong@cpu.edu.cn.
Luo J; State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. luojg@cpu.edu.cn lykong@cpu.edu.cn.
Kong L; State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China. luojg@cpu.edu.cn lykong@cpu.edu.cn.

Chem Commun (Camb) ; 55(57): 8231-8234, 2019 Jul 11.

Article em En | MEDLINE | ID: mdl-31241075

Assuntos

Corantes Fluorescentes/química; Pregnenos/análise; Proteômica/métodos; Linhagem Celular Tumoral; Cumarínicos/química; Humanos; Microscopia de Fluorescência; Pregnenos/metabolismo; ATPases Transportadoras de Cálcio do Retículo Sarcoplasmático/análise; ATPases Transportadoras de Cálcio do Retículo Sarcoplasmático/metabolismo

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Pregnenos / Proteômica / Corantes Fluorescentes Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Chem Commun (Camb) Assunto da revista: QUIMICA Ano de publicação: 2019 Tipo de documento: Article

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