GSDMD is required for effector CD8<sup>+</sup> T cell responses to lung cancer cells.

Xi, Guangmin; Gao, Jianwei; Wan, Bing; Zhan, Ping; Xu, Wujian; Lv, Tangfeng; Song, Yong

GSDMD is required for effector CD8⁺ T cell responses to lung cancer cells.

Xi, Guangmin; Gao, Jianwei; Wan, Bing; Zhan, Ping; Xu, Wujian; Lv, Tangfeng; Song, Yong.

Afiliação

Xi G; Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China; College of Life Science, Qi Lu Normal University, Jinan, Shandong 250012, China. Electronic address: 475810355@qq.com.
Gao J; Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China; Nanjing University Institute of Respiratory Medicine, Nanjing 210002, China.
Wan B; Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China; Nanjing University Institute of Respiratory Medicine, Nanjing 210002, China.
Zhan P; Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China; Nanjing University Institute of Respiratory Medicine, Nanjing 210002, China.
Xu W; Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China; Nanjing University Institute of Respiratory Medicine, Nanjing 210002, China.
Lv T; Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China; Nanjing University Institute of Respiratory Medicine, Nanjing 210002, China.
Song Y; Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China; Nanjing University Institute of Respiratory Medicine, Nanjing 210002, China. Electronic address: yong_song6310@yahoo.com.

Int Immunopharmacol ; 74: 105713, 2019 Sep.

Article em En | MEDLINE | ID: mdl-31276977

Assuntos

Linfócitos T CD8-Positivos/fisiologia; Peptídeos e Proteínas de Sinalização Intracelular/metabolismo; Neoplasias Pulmonares/metabolismo; Proteínas de Ligação a Fosfato/metabolismo; Animais; Linhagem Celular Tumoral; Citotoxicidade Imunológica/genética; Feminino; Regulação Neoplásica da Expressão Gênica; Perfil Genético; Humanos; Vigilância Imunológica; Peptídeos e Proteínas de Sinalização Intracelular/genética; Neoplasias Pulmonares/genética; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Proteínas de Ligação a Fosfato/genética; Piroptose/genética

Palavras-chave

CTL; GSDMD; Gasdermin family; Immune response; NSCLC

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Pulmao Base de dados: MEDLINE Assunto principal: Linfócitos T CD8-Positivos / Proteínas de Ligação a Fosfato / Peptídeos e Proteínas de Sinalização Intracelular / Neoplasias Pulmonares Limite: Animals / Female / Humans Idioma: En Revista: Int Immunopharmacol Assunto da revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Ano de publicação: 2019 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google