A Conserved Microbial Motif 'Traps' Protease Activation in Host Immunity.

Sabale, Mugdha; Di Pietro, Antonio; Redkar, Amey

Sabale, Mugdha; Di Pietro, Antonio; Redkar, Amey.

Afiliação

Sabale M; Department of Genetics, University of Córdoba, Córdoba 14071, Spain.
Di Pietro A; Department of Genetics, University of Córdoba, Córdoba 14071, Spain.
Redkar A; Department of Genetics, University of Córdoba, Córdoba 14071, Spain. Electronic address: ge2rerea@uco.es.

Trends Plant Sci ; 24(8): 665-667, 2019 08.

Article em En | MEDLINE | ID: mdl-31280986

RESUMO

A recent study (Misas-Villamil et al., Nat. Commun., 2019) reveals that Pit2, an apoplastic effector of the corn smut fungus Ustilago maydis, contains an embedded motif of 14 amino acids that binds to and inhibits plant cysteine proteases, thereby modulating host immunity. Intriguingly, the inhibitory motif acts by mimicking the protease substrate and is conserved across microbial kingdoms.

Assuntos

Ustilago; Peptídeo Hidrolases; Imunidade Vegetal; Zea mays

Palavras-chave

Ustilago maydis; apoplast; microbial inhibitor; papain-like cysteine proteases; substrate

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Ustilago Idioma: En Revista: Trends Plant Sci Assunto da revista: BOTANICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Espanha

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