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An ultrasonographic monitoring of skin condition in patients receiving radiotherapy for head and neck cancers.
Pazdrowski, Jakub; Danczak-Pazdrowska, Aleksandra; Polanska, Adriana; Kazmierska, Joanna; Barczak, Wojciech; Szewczyk, Mateusz; Golusinski, Pawel; Adamski, Zygmunt; Zaba, Ryszard; Golusinski, Wojciech.
Afiliação
  • Pazdrowski J; Department of Head and Neck Surgery, Poznan University of Medical Sciences, Poznan, Poland.
  • Danczak-Pazdrowska A; Department of Head and Neck Surgery, The Greater Poland Cancer Centre, Poznan, Poland.
  • Polanska A; Department of Dermatology, Poznan University of Medical Sciences, Poznan, Poland.
  • Kazmierska J; Department of Dermatology and Venereology, Poznan University of Medical Sciences, Poznan, Poland.
  • Barczak W; Radiotherapy Department, II Greater Poland Cancer Center, Poznan, Poland.
  • Szewczyk M; Electroradiology Department, University of Medical Sciences, Poznan, Poland.
  • Golusinski P; Department of Head and Neck Surgery, Poznan University of Medical Sciences, Poznan, Poland.
  • Adamski Z; Radiobiology Lab, The Greater Poland Cancer Centre, Poznan, Poland.
  • Zaba R; Department of Head and Neck Surgery, Poznan University of Medical Sciences, Poznan, Poland.
  • Golusinski W; Department of Head and Neck Surgery, The Greater Poland Cancer Centre, Poznan, Poland.
Skin Res Technol ; 25(6): 857-861, 2019 Nov.
Article em En | MEDLINE | ID: mdl-31338911
ABSTRACT
Radiodermatitis is one of the commonest side effects of radiotherapy. They are usually assessed by semi-quantitative clinical scores, which are not validated and may be subject to inter-observer variability. A few previous studies suggested that high-frequency ultrasonography (HF-USG) is useful in the assessment of the acute phase of radiation dermatitis in breast cancer patients. (a) To monitor skin changes by HF-USG during the course of radiotherapy due to head and neck cancers, and (b) to determine whether there is any connection between skin sonograms and the skin scoring criteria. This prospective, observational study includes patients diagnosed with head and neck cancers, treated with radiotherapy or concomitant chemoradiation. The final analysis includes six patients. In every patient, the HF-USG as well as dermatological assessment (target lesion score-TLS and CACE v. 4.0) were performed 4× before, in the middle, day after, and 3 months after radiotherapy. There were significant differences between non-irradiated skin thickness and thickness of skin with clinically obvious radiodermatitis (TLS grade 1-4; P < .0001), as well as between irradiated, unchanged skin thickness (TLS grade 0) and thickness of skin with clinically obvious radiodermatitis (TLS grade 1-4; P = .0002). There was no significant difference between non-irradiated and irradiated, unchanged skin thickness (TLS grade 0; P = .9318). In four patients, we demonstrated subepidermal low echogenic band (SLEB). HF-USG can be useful tool to noninvasive and objective assessment of skin changes during radiotherapy.
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos / Tratamento / Radioterapia Base de dados: MEDLINE Assunto principal: Radiodermite / Pele / Interpretação de Imagem Assistida por Computador / Ultrassonografia / Neoplasias de Cabeça e Pescoço Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Humans Idioma: En Revista: Skin Res Technol Assunto da revista: DERMATOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Polônia

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos / Tratamento / Radioterapia Base de dados: MEDLINE Assunto principal: Radiodermite / Pele / Interpretação de Imagem Assistida por Computador / Ultrassonografia / Neoplasias de Cabeça e Pescoço Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Humans Idioma: En Revista: Skin Res Technol Assunto da revista: DERMATOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Polônia