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Long-lasting blood pressure lowering effects of nitrite are NO-independent and mediated by hydrogen peroxide, persulfides, and oxidation of protein kinase G1α redox signalling.
Feelisch, Martin; Akaike, Takaaki; Griffiths, Kayleigh; Ida, Tomoaki; Prysyazhna, Oleksandra; Goodwin, Joanna J; Gollop, Nicholas D; Fernandez, Bernadette O; Minnion, Magdalena; Cortese-Krott, Miriam M; Borgognone, Alessandra; Hayes, Rosie M; Eaton, Philip; Frenneaux, Michael P; Madhani, Melanie.
Afiliação
  • Feelisch M; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, SO16 6YD, UK.
  • Akaike T; Department of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine, Sendai, 980-8575, Japan.
  • Griffiths K; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Ida T; Department of Environmental Medicine and Molecular Toxicology, Tohoku University Graduate School of Medicine, Sendai, 980-8575, Japan.
  • Prysyazhna O; King's College of London, School of Cardiovascular Medicine & Sciences, The British Heart Foundation Centre of Excellence, The Rayne Institute, St Thomas' Hospital, London, SE1 7EH, UK.
  • Goodwin JJ; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Gollop ND; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Fernandez BO; Norwich Medical School, University of East Anglia, Bob Champion Research and Education Building, Norwich Research Park, Norwich, NR4 7UQ, UK.
  • Minnion M; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, SO16 6YD, UK.
  • Cortese-Krott MM; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, SO16 6YD, UK.
  • Borgognone A; Division of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, Heinrich Heine University, Düsseldorf, 40225, Germany.
  • Hayes RM; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Eaton P; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
  • Frenneaux MP; King's College of London, School of Cardiovascular Medicine & Sciences, The British Heart Foundation Centre of Excellence, The Rayne Institute, St Thomas' Hospital, London, SE1 7EH, UK.
  • Madhani M; Norwich Medical School, University of East Anglia, Bob Champion Research and Education Building, Norwich Research Park, Norwich, NR4 7UQ, UK.
Cardiovasc Res ; 116(1): 51-62, 2020 01 01.
Article em En | MEDLINE | ID: mdl-31372656
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Nitrito de Sódio / Sulfetos / Vasodilatação / Vasodilatadores / Pressão Sanguínea / Proteína Quinase Dependente de GMP Cíclico Tipo I / Peróxido de Hidrogênio / Artérias Mesentéricas Limite: Animals Idioma: En Revista: Cardiovasc Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Nitrito de Sódio / Sulfetos / Vasodilatação / Vasodilatadores / Pressão Sanguínea / Proteína Quinase Dependente de GMP Cíclico Tipo I / Peróxido de Hidrogênio / Artérias Mesentéricas Limite: Animals Idioma: En Revista: Cardiovasc Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Reino Unido