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Novel multi target-directed ligands targeting 5-HT4 receptors with in cellulo antioxidant properties as promising leads in Alzheimer's disease.
Lanthier, Caroline; Payan, Hugo; Liparulo, Irene; Hatat, Bérénice; Lecoutey, Cédric; Since, Marc; Davis, Audrey; Bergamini, Christian; Claeysen, Sylvie; Dallemagne, Patrick; Bolognesi, Maria-Laura; Rochais, Christophe.
Afiliação
  • Lanthier C; Centre d'Etudes et de Recherche sur le Médicament de Normandie, Normandie Univ, UNICAEN, CERMN, 14000, Caen, France.
  • Payan H; IGF, Univ. Montpellier, CNRS, INSERM, Montpellier, France.
  • Liparulo I; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, I-40126, Bologna, Italy.
  • Hatat B; Centre d'Etudes et de Recherche sur le Médicament de Normandie, Normandie Univ, UNICAEN, CERMN, 14000, Caen, France; IGF, Univ. Montpellier, CNRS, INSERM, Montpellier, France.
  • Lecoutey C; Centre d'Etudes et de Recherche sur le Médicament de Normandie, Normandie Univ, UNICAEN, CERMN, 14000, Caen, France.
  • Since M; Centre d'Etudes et de Recherche sur le Médicament de Normandie, Normandie Univ, UNICAEN, CERMN, 14000, Caen, France.
  • Davis A; Centre d'Etudes et de Recherche sur le Médicament de Normandie, Normandie Univ, UNICAEN, CERMN, 14000, Caen, France.
  • Bergamini C; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, I-40126, Bologna, Italy.
  • Claeysen S; IGF, Univ. Montpellier, CNRS, INSERM, Montpellier, France.
  • Dallemagne P; Centre d'Etudes et de Recherche sur le Médicament de Normandie, Normandie Univ, UNICAEN, CERMN, 14000, Caen, France.
  • Bolognesi ML; Department of Pharmacy and Biotechnology, Alma Mater Studiorum, University of Bologna, I-40126, Bologna, Italy.
  • Rochais C; Centre d'Etudes et de Recherche sur le Médicament de Normandie, Normandie Univ, UNICAEN, CERMN, 14000, Caen, France. Electronic address: christophe.rochais@unicaen.fr.
Eur J Med Chem ; 182: 111596, 2019 Nov 15.
Article em En | MEDLINE | ID: mdl-31419776

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Receptores 5-HT4 de Serotonina / Agonistas do Receptor 5-HT4 de Serotonina / Antioxidantes Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: França

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Receptores 5-HT4 de Serotonina / Agonistas do Receptor 5-HT4 de Serotonina / Antioxidantes Limite: Animals / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: França