DNA methylation silencing of microRNA gene methylator in the precancerous background mucosa with and without gastric cancer: Analysis of the effects of H. pylori eradication and long-term aspirin use.

Watari, Jiro; Ito, Chiyomi; Shimoda, Tadakazu; Tomita, Toshihiko; Oshima, Tadayuki; Fukui, Hirokazu; Das, Kiron M; Miwa, Hiroto

Watari, Jiro; Ito, Chiyomi; Shimoda, Tadakazu; Tomita, Toshihiko; Oshima, Tadayuki; Fukui, Hirokazu; Das, Kiron M; Miwa, Hiroto.

Afiliação

Watari J; Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan. watarij@hyo-med.ac.jp.
Ito C; Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.
Shimoda T; Division of Pathology, Shizuoka Cancer Center, Shizuoka, 411-8777, Japan.
Tomita T; Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.
Oshima T; Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.
Fukui H; Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.
Das KM; Division of Gastroenterology and Hepatology, Departments of Medicine and Pathology, Robert Wood Johnson Medical School, Rutgers, Cancer Institute of New Jersey, New Brunswick, New Jersey, 08903, United States.
Miwa H; Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.

Sci Rep ; 9(1): 12559, 2019 08 29.

Article em En | MEDLINE | ID: mdl-31467363

Assuntos

Aspirina/farmacologia; Metilação de DNA/genética; Mucosa Gástrica/metabolismo; Helicobacter pylori/efeitos dos fármacos; MicroRNAs/genética; Lesões Pré-Cancerosas/genética; Neoplasias Gástricas/genética; Idoso; Estudos de Coortes; Feminino; Inativação Gênica; Helicobacter pylori/fisiologia; Humanos; Masculino; Pessoa de Meia-Idade; Lesões Pré-Cancerosas/microbiologia; Neoplasias Gástricas/microbiologia; Fatores de Tempo

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Estomago Base de dados: MEDLINE Assunto principal: Lesões Pré-Cancerosas / Neoplasias Gástricas / Aspirina / Helicobacter pylori / Metilação de DNA / MicroRNAs / Mucosa Gástrica Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Sci Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão

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