Sox9 Is a Modifier of the Liver Disease Severity in a Mouse Model of Alagille Syndrome.

Adams, Joshua M; Huppert, Kari A; Castro, Eumenia C; Lopez, Mario F; Niknejad, Nima; Subramanian, Sanjay; Zarrin-Khameh, Neda; Finegold, Milton J; Huppert, Stacey S; Jafar-Nejad, Hamed

Adams, Joshua M; Huppert, Kari A; Castro, Eumenia C; Lopez, Mario F; Niknejad, Nima; Subramanian, Sanjay; Zarrin-Khameh, Neda; Finegold, Milton J; Huppert, Stacey S; Jafar-Nejad, Hamed.

Afiliação

Adams JM; Program in Developmental Biology, Baylor College of Medicine, Houston, TX.
Huppert KA; Medical Scientist Training Program, Baylor College of Medicine, Houston, TX.
Castro EC; Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Lopez MF; Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX.
Niknejad N; Department of Pathology, Texas Children's Hospital, Houston, TX.
Subramanian S; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX.
Zarrin-Khameh N; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX.
Finegold MJ; Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Huppert SS; Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX.
Jafar-Nejad H; Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX.

Hepatology ; 71(4): 1331-1349, 2020 04.

Article em En | MEDLINE | ID: mdl-31469182

Assuntos

Síndrome de Alagille/genética; Síndrome de Alagille/patologia; Fígado/patologia; Fatores de Transcrição SOX9/genética; Animais; Ductos Biliares/anormalidades; Transdiferenciação Celular/genética; Criança; Pré-Escolar; Modelos Animais de Doenças; Hepatócitos/citologia; Heterozigoto; Humanos; Lactente; Proteína Jagged-1/genética; Fígado/anormalidades; Fígado/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; Receptores Notch/genética; Receptores Notch/metabolismo; Índice de Gravidade de Doença; Transdução de Sinais

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Síndrome de Alagille / Fatores de Transcrição SOX9 / Fígado Tipo de estudo: Prognostic_studies Limite: Animals / Child / Child, preschool / Humans / Infant Idioma: En Revista: Hepatology Ano de publicação: 2020 Tipo de documento: Article

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