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Celastrol-induced degradation of FANCD2 sensitizes pediatric high-grade gliomas to the DNA-crosslinking agent carboplatin.
Metselaar, Dennis S; Meel, Michaël H; Benedict, Bente; Waranecki, Piotr; Koster, Jan; Kaspers, Gertjan J L; Hulleman, Esther.
Afiliação
  • Metselaar DS; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Departments of Pediatric Oncology/Hematology, Emma Children's hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands.
  • Meel MH; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Departments of Pediatric Oncology/Hematology, Emma Children's hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands.
  • Benedict B; Division of Tumor Biology and Immunology, the Netherlands Cancer Institute, Amsterdam, the Netherlands.
  • Waranecki P; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Departments of Pediatric Oncology/Hematology, Emma Children's hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands.
  • Koster J; Department of Oncogenomics, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Kaspers GJL; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Departments of Pediatric Oncology/Hematology, Emma Children's hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands.
  • Hulleman E; Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Departments of Pediatric Oncology/Hematology, Emma Children's hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands. Electronic address: e.hulleman@prinsesmaximacentrum.nl.
EBioMedicine ; 50: 81-92, 2019 Dec.
Article em En | MEDLINE | ID: mdl-31735550
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Triterpenos / Carboplatina / Resistencia a Medicamentos Antineoplásicos / Reagentes de Ligações Cruzadas / Proteína do Grupo de Complementação D2 da Anemia de Fanconi / Glioma Tipo de estudo: Prognostic_studies Limite: Adolescent / Animals / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: EBioMedicine Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Holanda
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Outros_tipos Base de dados: MEDLINE Assunto principal: Triterpenos / Carboplatina / Resistencia a Medicamentos Antineoplásicos / Reagentes de Ligações Cruzadas / Proteína do Grupo de Complementação D2 da Anemia de Fanconi / Glioma Tipo de estudo: Prognostic_studies Limite: Adolescent / Animals / Child / Child, preschool / Female / Humans / Male Idioma: En Revista: EBioMedicine Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Holanda