Evolution of resistance in vitro reveals mechanisms of artemisinin activity in <i>Toxoplasma gondii</i>.

Rosenberg, Alex; Luth, Madeline R; Winzeler, Elizabeth A; Behnke, Michael; Sibley, L David

Evolution of resistance in vitro reveals mechanisms of artemisinin activity in Toxoplasma gondii.

Rosenberg, Alex; Luth, Madeline R; Winzeler, Elizabeth A; Behnke, Michael; Sibley, L David.

Afiliação

Rosenberg A; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.
Luth MR; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA 92093.
Winzeler EA; Department of Pediatrics, School of Medicine, University of California San Diego, La Jolla, CA 92093.
Behnke M; Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803.
Sibley LD; Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110.

Proc Natl Acad Sci U S A ; 116(52): 26881-26891, 2019 Dec 26.

Article em En | MEDLINE | ID: mdl-31806760

Palavras-chave

drug resistance; evolution; genome amplification; mitochondrion; mutation rate

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2019 Tipo de documento: Article

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