The local immune phenotype influences prognosis in patients with nodal-positive rectal cancer after neoadjuvant chemoradiation.

Schollbach, Julia; Kircher, Stefan; Wiegering, Armin; Anger, Friedrich; Rosenwald, Andreas; Germer, Christoph-Thomas; Löb, Stefan

Schollbach, Julia; Kircher, Stefan; Wiegering, Armin; Anger, Friedrich; Rosenwald, Andreas; Germer, Christoph-Thomas; Löb, Stefan.

Afiliação

Schollbach J; Department of General, Visceral, Transplantation, Vascular and Paediatric Surgery, University Hospital of Würzburg, Oberdürrbacherstr. 6, 97080, Würzburg, Germany.
Kircher S; Department of Pathology, University of Würzburg, Würzburg, Germany.
Wiegering A; Department of General, Visceral, Transplantation, Vascular and Paediatric Surgery, University Hospital of Würzburg, Oberdürrbacherstr. 6, 97080, Würzburg, Germany.
Anger F; Theodor Boveri Institute, Biocentre, University of Würzburg, Am Hubland, 97074, Würzburg, Germany.
Rosenwald A; Comprehensive Cancer Centre Mainfranken, University of Würzburg, Josef-Schneider-Str. 6, 97080, Würzburg, Germany.
Germer CT; Department of General, Visceral, Transplantation, Vascular and Paediatric Surgery, University Hospital of Würzburg, Oberdürrbacherstr. 6, 97080, Würzburg, Germany.
Löb S; Department of Pathology, University of Würzburg, Würzburg, Germany.

Int J Colorectal Dis ; 35(2): 365-370, 2020 Feb.

Article em En | MEDLINE | ID: mdl-31828368

Assuntos

Biomarcadores Tumorais/análise; Linfócitos T CD8-Positivos/imunologia; Indolamina-Pirrol 2,3,-Dioxigenase/análise; Linfócitos do Interstício Tumoral/imunologia; Neoplasias Retais/imunologia; Microambiente Tumoral; Adulto; Idoso; Idoso de 80 Anos ou mais; Quimiorradioterapia Adjuvante; Intervalo Livre de Doença; Feminino; Humanos; Imuno-Histoquímica; Metástase Linfática; Masculino; Pessoa de Meia-Idade; Terapia Neoadjuvante; Estadiamento de Neoplasias; Valor Preditivo dos Testes; Protectomia; Neoplasias Retais/mortalidade; Neoplasias Retais/patologia; Neoplasias Retais/terapia; Estudos Retrospectivos; Fatores de Risco; Fatores de Tempo

Palavras-chave

Adjuvant treatment strategies; Immune profile; Neoadjuvant therapy; Precision oncology; Rectal cancer; Survival

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Colon_e_reto Base de dados: MEDLINE Assunto principal: Neoplasias Retais / Biomarcadores Tumorais / Linfócitos do Interstício Tumoral / Linfócitos T CD8-Positivos / Indolamina-Pirrol 2,3,-Dioxigenase / Microambiente Tumoral Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Colorectal Dis Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Alemanha

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