Diverse Injury Pathways Induce Alveolar Epithelial Cell CCL2/12, Which Promotes Lung Fibrosis.

Yang, Jibing; Agarwal, Manisha; Ling, Song; Teitz-Tennenbaum, Seagal; Zemans, Rachel L; Osterholzer, John J; Sisson, Thomas H; Kim, Kevin K

Yang, Jibing; Agarwal, Manisha; Ling, Song; Teitz-Tennenbaum, Seagal; Zemans, Rachel L; Osterholzer, John J; Sisson, Thomas H; Kim, Kevin K.

Afiliação

Yang J; Unit for Lab Animal Medicine and.
Agarwal M; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan; and.
Ling S; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan; and.
Teitz-Tennenbaum S; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan; and.
Zemans RL; Pulmonary Section, Department of Medicine, VA Ann Arbor Health System, Ann Arbor, Michigan.
Osterholzer JJ; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan; and.
Sisson TH; Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan; and.
Kim KK; Pulmonary Section, Department of Medicine, VA Ann Arbor Health System, Ann Arbor, Michigan.

Am J Respir Cell Mol Biol ; 62(5): 622-632, 2020 05.

Article em En | MEDLINE | ID: mdl-31922885

Assuntos

Células Epiteliais Alveolares/metabolismo; Células Epiteliais Alveolares/patologia; Quimiocina CCL2/metabolismo; Lesão Pulmonar/complicações; Proteínas Quimioatraentes de Monócitos/metabolismo; Fibrose Pulmonar/etiologia; Fibrose Pulmonar/metabolismo; Animais; Deleção de Genes; Humanos; Macrófagos/metabolismo; Macrófagos/patologia; Camundongos Endogâmicos C57BL; Especificidade de Órgãos; Proteína Regulatória Associada a mTOR/metabolismo; Reprodutibilidade dos Testes; Transdução de Sinais; Serina-Treonina Quinases TOR/metabolismo

Palavras-chave

CCL12; CCL2; alveolar epithelial cell; fibrosis

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / Proteínas Quimioatraentes de Monócitos / Quimiocina CCL2 / Lesão Pulmonar / Células Epiteliais Alveolares Limite: Animals / Humans Idioma: En Revista: Am J Respir Cell Mol Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2020 Tipo de documento: Article

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