High expression of ID1 in monocytes is strongly associated with phenotypic and functional MDSC markers in advanced melanoma.

Melief, Jeroen; Pico de Coaña, Yago; Maas, Roeltje; Fennemann, Felix-Lennart; Wolodarski, Maria; Hansson, Johan; Kiessling, Rolf

Melief, Jeroen; Pico de Coaña, Yago; Maas, Roeltje; Fennemann, Felix-Lennart; Wolodarski, Maria; Hansson, Johan; Kiessling, Rolf.

Afiliação

Melief J; Department of Oncology-Pathology, Karolinska Institute, Visionsgatan 4, 171 64 Solna, Stockholm, Sweden. jeroen.melief@ki.se.
Pico de Coaña Y; Department of Oncology-Pathology, Karolinska Institute, Visionsgatan 4, 171 64 Solna, Stockholm, Sweden.
Maas R; Department of Oncology-Pathology, Karolinska Institute, Visionsgatan 4, 171 64 Solna, Stockholm, Sweden.
Fennemann FL; Department of Oncology, Ludwig Institute for Cancer Research, University of Lausanne, Lausanne, Switzerland.
Wolodarski M; Department of Oncology-Pathology, Karolinska Institute, Visionsgatan 4, 171 64 Solna, Stockholm, Sweden.
Hansson J; Department of Tumor Immunology, Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Kiessling R; Department of Oncology-Pathology, Karolinska Institute, Visionsgatan 4, 171 64 Solna, Stockholm, Sweden.

Cancer Immunol Immunother ; 69(4): 513-522, 2020 Apr.

Article em En | MEDLINE | ID: mdl-31953577

Assuntos

Biomarcadores/metabolismo; Proteína 1 Inibidora de Diferenciação/metabolismo; Melanoma/metabolismo; Monócitos/metabolismo; Células Supressoras Mieloides/metabolismo; Adulto; Idoso; Idoso de 80 Anos ou mais; Animais; Linhagem Celular Tumoral; Células Cultivadas; Feminino; Antígenos HLA-DR/metabolismo; Humanos; Masculino; Melanoma/sangue; Melanoma/cirurgia; Camundongos; Pessoa de Meia-Idade; Fenótipo

Palavras-chave

Cancer; Immunosuppression; Melanoma; Myeloid cells

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Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Pele Base de dados: MEDLINE Assunto principal: Monócitos / Biomarcadores / Proteína 1 Inibidora de Diferenciação / Células Supressoras Mieloides / Melanoma Tipo de estudo: Risk_factors_studies Limite: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Cancer Immunol Immunother Assunto da revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Suécia

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