Particulate matter (PM10) induces cardiovascular developmental toxicity in zebrafish embryos and larvae via the ERS, Nrf2 and Wnt pathways.

Cen, Juan; Jia, Zhi-Li; Zhu, Cheng-Yue; Wang, Xue-Fang; Zhang, Feng; Chen, Wei-Yun; Liu, Ke-Chun; Li, Sai-Yu; Zhang, Yun

Cen, Juan; Jia, Zhi-Li; Zhu, Cheng-Yue; Wang, Xue-Fang; Zhang, Feng; Chen, Wei-Yun; Liu, Ke-Chun; Li, Sai-Yu; Zhang, Yun.

Afiliação

Cen J; Key Laboratory of Natural Medicine and Immuno-Engineering, Henan University, Kaifeng, Henan Province, PR China.
Jia ZL; Key Laboratory of Natural Medicine and Immuno-Engineering, Henan University, Kaifeng, Henan Province, PR China; Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, Shandong Province, PR China.
Zhu CY; Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, Shandong Province, PR China.
Wang XF; Jigang Hospital, Jinan, Shandong Province, PR China.
Zhang F; College of Pharmacy, Henan University, Kaifeng, Henan Province, PR China.
Chen WY; Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, Shandong Province, PR China.
Liu KC; Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, Shandong Province, PR China.
Li SY; Shandong Analysis and Test Center, Jinan, Shandong Province, PR China. Electronic address: cszxli@163.com.
Zhang Y; Biology Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan, Shandong Province, PR China. Electronic address: xiaohan_0818@163.com.

Chemosphere ; 250: 126288, 2020 Jul.

Article em En | MEDLINE | ID: mdl-32114347

Assuntos

Sistema Cardiovascular/efeitos dos fármacos; Embrião não Mamífero/efeitos dos fármacos; Larva/efeitos dos fármacos; Material Particulado/toxicidade; Animais; Larva/metabolismo; Fator 2 Relacionado a NF-E2/efeitos dos fármacos; Fator 2 Relacionado a NF-E2/metabolismo; Organogênese; Espécies Reativas de Oxigênio/metabolismo; Via de Sinalização Wnt/efeitos dos fármacos; Peixe-Zebra/metabolismo; Proteínas de Peixe-Zebra/genética

Palavras-chave

Cardiovascular toxicity; ERS; Nrf2; PM10; Wnt

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Sistema Cardiovascular / Embrião não Mamífero / Material Particulado / Larva Limite: Animals Idioma: En Revista: Chemosphere Ano de publicação: 2020 Tipo de documento: Article

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