CD29 identifies IFN-Î³-producing human CD8<sup>+</sup> T cells with an increased cytotoxic potential.

Nicolet, Benoît P; Guislain, Aurélie; van Alphen, Floris P J; Gomez-Eerland, Raquel; Schumacher, Ton N M; van den Biggelaar, Maartje; Wolkers, Monika C

CD29 identifies IFN-Î³-producing human CD8⁺ T cells with an increased cytotoxic potential.

Nicolet, Benoît P; Guislain, Aurélie; van Alphen, Floris P J; Gomez-Eerland, Raquel; Schumacher, Ton N M; van den Biggelaar, Maartje; Wolkers, Monika C.

Afiliação

Nicolet BP; Department of Hematopoiesis, Sanquin Research, 1066 CX Amsterdam, The Netherlands.
Guislain A; Landsteiner Laboratory, Oncode Institute, Amsterdam University Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
van Alphen FPJ; Department of Hematopoiesis, Sanquin Research, 1066 CX Amsterdam, The Netherlands.
Gomez-Eerland R; Landsteiner Laboratory, Oncode Institute, Amsterdam University Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
Schumacher TNM; Department of Research Facilities, Sanquin Research, 1066 CX Amsterdam, The Netherlands.
van den Biggelaar M; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
Wolkers MC; Division of Molecular Oncology and Immunology, Oncode Institute, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.

Proc Natl Acad Sci U S A ; 117(12): 6686-6696, 2020 03 24.

Article em En | MEDLINE | ID: mdl-32161126

Assuntos

Linfócitos T CD8-Positivos/imunologia; Citotoxicidade Imunológica/imunologia; Integrina beta1/metabolismo; Interferon gama/metabolismo; Interleucina-2/metabolismo; Melanoma/patologia; Linfócitos T Citotóxicos/imunologia; Perfilação da Expressão Gênica; Humanos; Melanoma/imunologia; Melanoma/metabolismo; Prognóstico; Neoplasias Cutâneas/imunologia; Neoplasias Cutâneas/metabolismo; Neoplasias Cutâneas/patologia; Taxa de Sobrevida

Palavras-chave

CD29; IFN-Î³; IL-2; T cells; cytotoxicity

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral / Tipos_de_cancer / Pele Base de dados: MEDLINE Assunto principal: Linfócitos T Citotóxicos / Interferon gama / Interleucina-2 / Linfócitos T CD8-Positivos / Integrina beta1 / Citotoxicidade Imunológica / Melanoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Holanda

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google