Inhibition of the Ubiquitin-Activating Enzyme UBA1 Suppresses Diet-Induced Atherosclerosis in Apolipoprotein E-Knockout Mice.

Liao, Jiawei; Yang, Xiaolei; Lin, Qiuyue; Liu, Shuang; Xie, Yunpeng; Xia, Yunlong; Li, Hui-Hua

Liao, Jiawei; Yang, Xiaolei; Lin, Qiuyue; Liu, Shuang; Xie, Yunpeng; Xia, Yunlong; Li, Hui-Hua.

Afiliação

Liao J; Department of Cardiology, Institute of Cardiovascular Diseases, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.
Yang X; Department of Cardiology, Institute of Cardiovascular Diseases, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.
Lin Q; Department of Cardiology, Institute of Cardiovascular Diseases, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.
Liu S; Department of Occupational and Environmental Health, School of Public Health, Dalian Medical University, Dalian 116011, China.
Xie Y; Department of Cardiology, Institute of Cardiovascular Diseases, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.
Xia Y; Department of Cardiology, Institute of Cardiovascular Diseases, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.
Li HH; Department of Cardiology, Institute of Cardiovascular Diseases, First Affiliated Hospital of Dalian Medical University, Dalian 116011, China.

J Immunol Res ; 2020: 7812709, 2020.

Article em En | MEDLINE | ID: mdl-32258175

Assuntos

Aterosclerose/metabolismo; Macrófagos/imunologia; Enzimas Ativadoras de Ubiquitina/metabolismo; Animais; Apolipoproteínas E/genética; Benzoatos/administração & dosagem; Benzoatos/farmacologia; Citocinas/metabolismo; Dieta Hiperlipídica; Modelos Animais de Doenças; Furanos/administração & dosagem; Furanos/farmacologia; Humanos; Mediadores da Inflamação/metabolismo; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Terapia de Alvo Molecular; Estresse Oxidativo; Pirazóis/administração & dosagem; Pirazóis/farmacologia; Células RAW 264.7; Enzimas Ativadoras de Ubiquitina/antagonistas & inibidores

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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: Enzimas Ativadoras de Ubiquitina / Aterosclerose / Macrófagos Limite: Animals / Humans / Male Idioma: En Revista: J Immunol Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

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