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Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope.
Jiang, Tingting; Henderson, Jordana M; Coote, Kevin; Cheng, Yi; Valley, Hillary C; Zhang, Xiao-Ou; Wang, Qin; Rhym, Luke H; Cao, Yueying; Newby, Gregory A; Bihler, Hermann; Mense, Martin; Weng, Zhiping; Anderson, Daniel G; McCaffrey, Anton P; Liu, David R; Xue, Wen.
Afiliação
  • Jiang T; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
  • Henderson JM; TriLink BioTechnologies, San Diego, CA, USA.
  • Coote K; Cystic Fibrosis Foundation, CFFT Lab, Lexington, MA, 02421, USA.
  • Cheng Y; Cystic Fibrosis Foundation, CFFT Lab, Lexington, MA, 02421, USA.
  • Valley HC; Cystic Fibrosis Foundation, CFFT Lab, Lexington, MA, 02421, USA.
  • Zhang XO; Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Wang Q; School of Life Sciences and Technology, Tongji University, 200092, Shanghai, China.
  • Rhym LH; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Cao Y; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
  • Newby GA; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
  • Bihler H; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA, USA.
  • Mense M; Howard Hughes Medical Institute, Harvard University, Cambridge, MA, 02138, USA.
  • Weng Z; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, 02138, USA.
  • Anderson DG; Cystic Fibrosis Foundation, CFFT Lab, Lexington, MA, 02421, USA.
  • McCaffrey AP; Cystic Fibrosis Foundation, CFFT Lab, Lexington, MA, 02421, USA.
  • Liu DR; Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, MA, USA.
  • Xue W; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
Nat Commun ; 11(1): 1979, 2020 04 24.
Article em En | MEDLINE | ID: mdl-32332735
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Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: RNA Mensageiro / Adenina / RNA Guia de Cinetoplastídeos / Sistemas CRISPR-Cas Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Temas: Geral Base de dados: MEDLINE Assunto principal: RNA Mensageiro / Adenina / RNA Guia de Cinetoplastídeos / Sistemas CRISPR-Cas Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos